Efficient racemization of 1-phenylethylamine and its derivatives

被引：3
作者：
Xiong, Xiaoxia [1 ]
Xu, Xinliang [2 ]
Zhou, Yifeng [1 ,2 ]
Weng, Chenchen [1 ]
机构：
[1] China Jiliang Univ, Coll Life Sci, Zhejiang Prov Key Lab Biometrol & Inspect & Quara, Hangzhou 310018, Zhejiang, Peoples R China
[2] Zhejiang Apeloa Med Technol Co Ltd, Dongyang 322118, Zhejiang, Peoples R China
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2013年 / 83卷 / 12期
关键词：
DYNAMIC KINETIC RESOLUTION; RADICAL-MEDIATED RACEMIZATION; PRIMARY AMINES; PD; CATALYSIS; ALCOHOLS; LIPASE; METAL;
D O I：
10.1134/S1070363213120359
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report on simple and efficient procedure for the racemization of 1-phenylethylamine and its derivatives. In the presence of trichloroisocyanuric acid, N-chloroimine derivative is formed as the intermediates, with subsequent hydrogenation catalyzed by Pd-C leading to the racemic product.
引用
收藏
页码：2402 / 2405
页数：4
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