A one-pot stereoselective synthesis of novel polyfunctionalized imidazolidines

被引：15

作者：

Olyaei, Abolfazl ^{[1
]}

Karimi, Mohsen Karbalaei ^{[1
]}

Razeghi, Reza ^{[1
]}

机构：

[1] Payame Noor Univ, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 42期

关键词：

Heteroarylamine; Aldehyde; Imidazolidine; Glyoxal; SOLVENT-FREE CONDITIONS; BIS-SCHIFF BASES; GLYOXAL; FORMALDEHYDE; DERIVATIVES; CONVENIENT; PRODUCTS; AMINES;

D O I：

10.1016/j.tetlet.2013.08.029

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile, one-pot stereoselective synthesis of novel trans-4,5-dihydroxy-2-aryl-1,3-bis(heteroaryl)imidazolidines is achieved by a cyclocondensation reaction of 2 equiv of heteroarylamines with benzaldehyde derivatives, in the presence of guanidinium chloride as a polyfunctional organocatalyst, with aqueous glyoxal to afford the title products. This general protocol provides a wide range of new polyfunctionalized imidazolidines in good to high yields. (C) 2013 Elsevier Ltd. All rights reserved.

引用

收藏

页码：5730 / 5733

页数：4

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