Effects of Chronic Exercise Training on Inflammatory Markers in Australian Overweight and Obese Individuals in a Randomized Controlled Trial

被引：36
作者：
Ho, Suleen S. [1 ]
Dhaliwal, Satvinder S. [1 ]
Hills, Andrew P. [2 ]
Pal, Sebely [1 ]
机构：
[1] Curtin Univ, Sch Publ Hlth, Curtin Hlth Innovat Res Inst, Perth, WA 6845, Australia
[2] Griffith Univ, Mater Med Res Inst, Conjoint Appointment Griffith Hlth Inst, Mater Mothers Hosp, South Brisbane, Qld 4101, Australia
来源：
INFLAMMATION | 2013年 / 36卷 / 03期
关键词：
obesity; overweight; tumor necrosis factor-alpha; interleukin-6; exercise training; NECROSIS-FACTOR-ALPHA; CHRONIC HEART-FAILURE; C-REACTIVE PROTEIN; WEIGHT-LOSS; INSULIN SENSITIVITY; METABOLIC SYNDROME; GLUCOSE-TOLERANCE; PHYSICAL-ACTIVITY; ADIPOKINE LEVELS; PLASMA-LEVELS;
D O I：
10.1007/s10753-012-9584-9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Physical activity has been shown to lower levels of inflammatory markers. However, results are inconsistent, indicating different modes of exercise may have different effects on inflammatory cytokines. We aimed to investigate the effects of 12 weeks of moderate-intensity aerobic, resistance, or combination exercise on TNF-alpha and IL-6 compared to no exercise in overweight and obese individuals. TNF-alpha levels were significantly decreased at week 12 compared to baseline by 20.8 % in the Aerobic group (p = 0.011), 26.9 % in the Resistance group (p = 0.0001), and 32.6 % in the Combination group (p = 0.003). Levels of TNF-alpha were significantly lower in the Combination compared to the Control group after 12 weeks of exercise training (-22.6 %, p = 0.025) when adjusting for baseline levels. Twelve weeks of moderate-intensity aerobic, resistance, but mainly combination exercise training decreased TNF-alpha in overweight and obese individuals compared to no exercise. Therefore, combination exercise training may be physiologically relevant in decreasing the risk of developing chronic diseases.
引用
收藏
页码：625 / 632
页数：8
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