Effects of X- and UV-irradiation on proteins

被引:27
作者
Durchschlag, H [1 ]
Fochler, C [1 ]
Feser, B [1 ]
Hausmann, S [1 ]
Seroneit, T [1 ]
Swientek, M [1 ]
Swoboda, E [1 ]
Winklmair, A [1 ]
Wlcek, C [1 ]
Zipper, P [1 ]
机构
[1] GRAZ UNIV,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
来源
RADIATION PHYSICS AND CHEMISTRY | 1996年 / 47卷 / 03期
关键词
D O I
10.1016/0969-806X(95)00138-N
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The radiation damage of several proteins has been investigated in aqueous solution, after preceding X- or UV-irradiation. In order to differentiate between different radiation effects, a series of physico-chemical and biochemical methods as well as novel evaluation and normalization procedures have been applied. Numerous changes of several molecular parameters characterizing functional ability and primary, secondary, tertiary and quaternary structure of proteins could be found. Modifications of radiation effects were achieved by a variety of measures and additives. The results are of interest for many fields of research using X-rays or UV light.
引用
收藏
页码:501 / 505
页数:5
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