Synthesis of 1,2-Diaryl-1H-indol-4-ols and 1,2-Diaryl-7-ethoxy-1,5,6,7-tetrahydroindol-4-ones from Arylglyoxals and Enamines through Domino Reactions

被引：22

作者：

Maity, Subhendu ^{[1
]}

Pathak, Sudipta ^{[1
]}

Pramanik, Animesh ^{[1
]}

机构：

[1] Univ Calcutta, Dept Chem, Kolkata 700009, India

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 2013卷 / 12期

关键词：

Synthetic methods; Domino reactions; Annulation; Nitrogen heterocycles; CATALYZED SYNTHESIS; INDOLES; DERIVATIVES; CYCLIZATION; CASCADE; CYCLOISOMERIZATION; ACTIVATION; INHIBITORS; AMINATION; ARYLATION;

D O I：

10.1002/ejoc.201201616

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 1,2-diaryl- and 1-alkyl-2-aryl-1H-indol-4-ols and 1,2-diaryl-7-ethoxy-1,5,6,7-tetrahydroindol-4-ones have been prepared by the domino reactions of arylglyoxals and enamines at reflux in non-nucleophilic and nucleophilic solvents such as acetonitrile and ethanol, respectively. The transformation occurs by annulation followed by aromatization without the use of any metal or catalyst.

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页码：2479 / 2485

页数：7

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