Testing Platelet Function

被引:49
|
作者
Harrison, Paul [1 ]
Lordkipanidze, Marie [2 ]
机构
[1] Univ Birmingham, Sch Med, Sch Immun & Infect, Birmingham B15 2TT, W Midlands, England
[2] Univ Birmingham, Coll Med & Dent Sci, Inst Biomed Res, Ctr Cardiovasc Sci, Birmingham B15 2TT, W Midlands, England
关键词
Platelets; Platelet function; Bleeding time; Platelet aggregation; Antiplatelet drugs; LIGHT TRANSMISSION AGGREGOMETRY; GLYCOPROTEIN IIB/IIIA ANTAGONISTS; BLOOD IMPEDANCE AGGREGOMETRY; VON-WILLEBRAND-FACTOR; LOW-DOSE ASPIRIN; WHOLE-BLOOD; FUNCTION ANALYZER; ANTIPLATELET THERAPY; PLATE(LET) ANALYZER; FLOW-CYTOMETRY;
D O I
10.1016/j.hoc.2013.03.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Platelet function tests have been traditionally used to aid in the diagnosis and management of patients with bleeding problems. Given the role of platelets in atherothrombosis, several dedicated platelet function instruments are now available that are simple to use and can be used as point-of-care assays. These can provide rapid assessment of platelet function within whole blood without the requirement of sample processing. Some tests can be used to monitor antiplatelet therapy and assess risk of bleeding and thrombosis, although current guidelines advise against this. This article discusses the potential utility of tests/instruments that are available.
引用
收藏
页码:411 / +
页数:32
相关论文
共 50 条
  • [41] Value of platelet function testing in monitoring platelet substitution
    Meyer, Oliver
    Kiesewetter, Holger
    Salama, Abdulgabar
    TRANSFUSION MEDICINE AND HEMOTHERAPY, 2007, 34 (06) : 389 - 393
  • [42] Platelet function in dogs with congenital portosystemic shunt
    Kalbantner, K.
    Meyer-Lindenberg, A.
    Mischke, R.
    VETERINARY JOURNAL, 2011, 188 (02) : 189 - 192
  • [43] Platelet function testing: from routine to specialist testing
    Gurney, David
    BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 2016, 73 (01) : 10 - 20
  • [44] Platelet Function Testing in Atherothrombotic Disease
    Grove, Erik Lerkevang
    Storey, Robert F.
    Wurtz, Morten
    CURRENT PHARMACEUTICAL DESIGN, 2012, 18 (33) : 5379 - 5391
  • [45] Any future for platelet function testing?
    Cuisset, Thomas
    SANG THROMBOSE VAISSEAUX, 2012, 24 (08): : 371 - 376
  • [46] Platelet Function Testing: A Role for Personalised Therapy in Coronary Disease
    Farag, Mohamed
    Gorog, Diana A.
    CURRENT PHARMACEUTICAL DESIGN, 2017, 23 (09) : 1315 - 1327
  • [47] Platelet function testing in cardiovascular diseases
    Michelson, AD
    HEMATOLOGY, 2005, 10 : 132 - 137
  • [48] Tests of platelet function
    Shah, Usman
    Ma, Alice D.
    CURRENT OPINION IN HEMATOLOGY, 2007, 14 (05) : 432 - 437
  • [49] Neonatal Platelet Function
    Del Vecchio, Antonio
    Motta, Mario
    Romagnoli, Costantino
    CLINICS IN PERINATOLOGY, 2015, 42 (03) : 625 - +
  • [50] Direct evidence for normalization of platelet function resulting from platelet count reduction in essential thrombocythemia
    Tsantes, Argirios E.
    Nikolopoulos, Georgios K.
    Tsirigotis, Panagiotis
    Zoi, Katerina
    Zomas, Athanasios
    Kapsimali, Violetta
    Kopterides, Petros
    Chondropoulos, Spyros
    Dervenoulas, John
    Mantzios, Georgios
    BLOOD COAGULATION & FIBRINOLYSIS, 2011, 22 (06) : 457 - 462