PET-CT in Clinical Adult Oncology: I. Hematologic Malignancies

被引:11
作者
Salem, Ahmed Ebada [1 ,2 ]
Shah, Harsh R. [3 ]
Covington, Matthew F. [1 ]
Koppula, Bhasker R. [1 ]
Fine, Gabriel C. [1 ]
Wiggins, Richard H. [1 ]
Hoffman, John M. [1 ]
Morton, Kathryn A. [1 ,4 ]
机构
[1] Univ Utah, Dept Radiol & Imaging Sci, Salt Lake City, UT 84132 USA
[2] Alexandria Univ, Fac Med, Dept Radiodiag & Intervent, Alexandria 21526, Egypt
[3] Univ Utah, Huntsman Canc Inst, Dept Med, Div Hematol, Salt Lake City, UT 84132 USA
[4] Intermt Healthcare Hosp, Murray, UT 84123 USA
关键词
imaging; FDG; positron emission tomography; PET; lymphoma; leukemia; multiple myeloma; B-cell lymphoma; T-cell lymphoma; POSITRON-EMISSION-TOMOGRAPHY; B-CELL LYMPHOMA; METABOLIC TUMOR VOLUME; STAGE HODGKINS LYMPHOMA; BONE-MARROW INVOLVEMENT; FDG-PET/CT; FOLLICULAR LYMPHOMA; PROGNOSTIC VALUE; INTERNATIONAL WORKSHOP; COMPUTED-TOMOGRAPHY;
D O I
10.3390/cancers14235941
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Simple Summary Positron emission tomography (PET); typically combined with computed tomography (CT), has become a critical advanced imaging technique in oncology. With PET-CT; a radioactive molecule (radiotracer) is injected in the bloodstream and localizes to sites of tumor because of specific cellular features of the tumor that accumulate the targeting radiotracer. The CT scan; performed at the same time; facilitates better visualization of radioactivity from deep or dense structures; and to provide detailed anatomic information. PET-CT has a variety of applications in oncology, including staging, therapeutic response assessment, restaging, and evaluation of suspected recurrence. This series of six articles provides an overview of the value, applications, and imaging and interpretive strategies of PET-CT in the more common adult malignancies. The current article addresses the use of PET-CT in hematologic malignancies. PET-CT is an advanced imaging modality with many oncologic applications, including staging, assessment of response to therapy, restaging and evaluation of suspected recurrence. The goal of this 6-part series of review articles is to provide practical information to providers and imaging professionals regarding the best use of PET-CT for the more common adult malignancies. In the first article of this series, hematologic malignancies are addressed. The classification of these malignancies will be outlined, with the disclaimer that the classification of lymphomas is constantly evolving. Critical applications, potential pitfalls, and nuances of PET-CT imaging in hematologic malignancies and imaging features of the major categories of these tumors are addressed. Issues of clinical importance that must be reported by the imaging professionals are outlined. The focus of this article is on [F-18] fluorodeoxyglucose (FDG), rather that research tracers or those requiring a local cyclotron. This information will serve as a resource for the appropriate role and limitations of PET-CT in the clinical management of patients with hematological malignancy for health care professionals caring for adult patients with hematologic malignancies. It also serves as a practical guide for imaging providers, including radiologists, nuclear medicine physicians and their trainees.
引用
收藏
页数:34
相关论文
共 127 条
[1]   Proportion of false-positive lesions at interim and end-of-treatment FDG-PET in lymphoma as determined by histology: Systematic review and meta-analysis [J].
Adams, Hugo J. A. ;
Kwee, Thomas C. .
EUROPEAN JOURNAL OF RADIOLOGY, 2016, 85 (11) :1963-1970
[2]   A Systematic Review of the Factors Affecting Accuracy of SUV Measurements [J].
Adams, Michael C. ;
Turkington, Timothy G. ;
Wilson, Joshua M. ;
Wong, Terence Z. .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2010, 195 (02) :310-320
[3]   Evolving Role of FDG PET/CT in Multiple Myeloma Imaging and Management [J].
Agarwal, Ankit ;
Chirindel, Alin ;
Shah, Bhartesh A. ;
Subramaniam, Rathan M. .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2013, 200 (04) :884-890
[4]   Whole-Body Magnetic Resonance Imaging: Current Role in Patients with Lymphoma [J].
Albano, Domenico ;
Micci, Giuseppe ;
Patti, Caterina ;
Midiri, Federico ;
Albano, Silvia ;
Lo Re, Giuseppe ;
Grassedonio, Emanuele ;
La Grutta, Ludovico ;
Lagalla, Roberto ;
Galia, Massimo .
DIAGNOSTICS, 2021, 11 (06)
[5]   Prognostic Value of 18F-FDG PET/CT Metabolic Parameters in Splenic Marginal Zone Lymphoma [J].
Albano, Domenico ;
Camoni, Luca ;
Giubbini, Raffaele ;
Bertagna, Francesco .
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2020, 20 (11) :E897-E904
[6]   Digital PET/CT allows for shorter acquisition protocols or reduced radiopharmaceutical dose in [18F]-FDG PET/CT [J].
Alberts, Ian ;
Sachpekidis, Christos ;
Prenosil, George ;
Viscione, Marco ;
Bohn, Karl Peter ;
Mingels, Clemens ;
Shi, Kuangyu ;
Ashar-Oromieh, Ali ;
Rominger, Axel .
ANNALS OF NUCLEAR MEDICINE, 2021, 35 (04) :485-492
[7]   Multimodality imaging of indolent B cell lymphoma from diagnosis to transformation: what every radiologist should know [J].
Alessandrino, Francesco ;
DiPiro, Pamela J. ;
Jagannathan, Jyothi P. ;
Babina, Gosangi ;
Krajewski, Katherine M. ;
Ramaiya, Nikhil H. ;
Giardino, Angela A. .
INSIGHTS INTO IMAGING, 2019, 10 (01)
[8]   Early Positron Emission Tomography Response-Adapted Treatment in Stage I and II Hodgkin Lymphoma: Final Results of the Randomized EORTC/LYSA/FIL H10 Trial [J].
Andre, Marc P. E. ;
Girinsky, Theodore ;
Federico, Massimo ;
Reman, Oumedaly ;
Fortpied, Catherine ;
Gotti, Manuel ;
Casasnovas, Olivier ;
Brice, Pauline ;
van der Maazen, Richard ;
Re, Alessandro ;
Edeline, Veronique ;
Ferme, Christophe ;
van Imhoff, Gustaaf ;
Merli, Francesco ;
Bouabdallah, Reda ;
Sebban, Catherine ;
Specht, Lena ;
Stamatoullas, Aspasia ;
Delarue, Richard ;
Fiaccadori, Valeria ;
Bellei, Monica ;
Raveloarivahy, Tiana ;
Versari, Annibale ;
Hutchings, Martin ;
Meignan, Michel ;
Raemaekers, John .
JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (16) :1786-+
[9]   Highly iodinated intravenous contrast material for PET/CT - a feasibility study [J].
不详 .
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 2008, 180 (08) :740-745
[10]   Overall Survival with Brentuximab Vedotin in Stage III or IV Hodgkin's Lymphoma [J].
Ansell, Stephen M. ;
Radford, John ;
Connors, Joseph M. ;
Dlugosz-Danecka, Monika ;
Kim, Won-Seog ;
Gallamini, Andrea ;
Ramchandren, Radhakrishnan ;
Friedberg, Jonathan W. ;
Advani, Ranjana ;
Hutchings, Martin ;
Evens, Andrew M. ;
Smolewski, Piotr ;
Savage, Kerry J. ;
Bartlett, Nancy L. ;
Eom, Hyeon-Seok ;
Abramson, Jeremy S. ;
Dong, Cassie ;
Campana, Frank ;
Fenton, Keenan ;
Puhlmann, Markus ;
Straus, David J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2022, 387 (04) :310-320