Mild copper(I) iodide/β-keto ester catalyzed coupling reactions of styryl bromides with phenols, thiophenols, and imidazoles

被引：38

作者：

Bao, Weiliang ^{[1
]}

Liu, Yunyun ^{[1
]}

Lv, Xin ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Zhejiang, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2008年 / 12期

关键词：

beta-keto esters; Ullmann coupling reaction; copper catalysis; vinylation;

D O I：

10.1055/s-2008-1067082

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and mild vinylation of O-, S-, and N-nucleophiles is reported. Copper(I) iodide/ethyl 2-oxocyclohexanecarboxylate is used as the catalytic system. The protocol tolerates a broad range of functional groups on the substrates, and gives the corresponding aryl styryl ethers, aryl styryl sulfides, and N-styrylimidazoles in moderate to excellent yields as well as with good stereoselectivity.

引用

页码：1911 / 1917

页数：7

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