EFFICIENT ONE-POT, FOUR-COMPONENT SYNTHESIS OF 1,2,3-TRIAZOLE-LINKED TETRAHYDROBENZO[b]PYRANS

被引:3
|
作者
MaGee, David I. [1 ]
Salehi, Peyman [2 ]
Dabiri, Minoo [3 ]
Bahramnejad, Mahboobeh [3 ]
机构
[1] Univ New Brunswick, Dept Chem, Fredericton, NB E3B 5A3, Canada
[2] Shahid Beheshti Univ Med Sci, Dept Phytochem, Med Plants & Drugs Res Inst, Tehran, Iran
[3] Shahid Beheshti Univ Med Sci, Fac Sci, Dept Chem, Tehran, Iran
基金
加拿大自然科学与工程研究理事会;
关键词
1,3-Dipolar cycloaddition; 4H-benzo[b]pyrans; multicomponent reaction; 1,2,3-triazoles; CLICK CHEMISTRY; DERIVATIVES; MULTICOMPONENT; 3-COMPONENT; CATALYST; AZIDE;
D O I
10.1080/00397911.2011.602813
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A one-pot procedure has been developed for the synthesis of (1,2,3-triazolyl) methoxyphenyl tetrahydro-5-oxo-4H-chromene derivatives by concurrent reaction of aryloxy propargylated aldehydes, various azides, active methylene compounds, and 1,3-cyclohexanediones using catalytic amounts of Cu(OAc)(2) / sodium ascorbate and diammonium hydrogen phosphate in aqueous ethanol media. Excellent conversion of starting materials was achieved to the desired (1,2,3-triazolyl) methoxyphenyl tetrahydro-5-oxo-4H-chromene products.
引用
收藏
页码:486 / 497
页数:12
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