Patagonicoside A:: a novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus

被引：40
作者：
Murray, AP
Muniaín, C
Seldes, AM
Maier, MS
机构：
[1] Fac Ciencias Exactas & Nat Buenos Aires, Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina
[2] Univ Nacl Sur, Dept Quim, RA-8000 Bahia Blanca, Buenos Aires, Argentina
[3] Museo Argentino Ciencias Nat Bernardino Rivadavia, RA-1405 Buenos Aires, DF, Argentina
来源：
TETRAHEDRON | 2001年 / 57卷 / 47期
关键词：
Psolus patagonicus; Holothuroidea; glycosides; triterpenes; antifungal activity;
D O I：
10.1016/S0040-4020(01)00970-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new triterpene glycoside, patagonicoside A (1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (H-1-, C-13-, H-1-H-1 COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide with a new aglycon moiety. Patagonicoside A (1) exhibits considerable antifungal activity against the pathogenic fungus Cladosporium cucumerinum. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：9563 / 9568
页数：6
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