Preventing lysosomal fat indigestion

被引：8

作者：

Cuervo, Ana Maria ^{[1
,1
]}

机构：

[1] Albert Einstein Coll Med, Inst Aging Studies, Bronx, NY 10461 USA

来源：

NATURE CELL BIOLOGY | 2013年 / 15卷 / 06期

关键词：

LIPID-METABOLISM; AUTOPHAGY; TFEB;

D O I：

10.1038/ncb2778

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Autophagy contributes to lipid catabolism through direct mobilization and breakdown of cellular lipid stores. Two recent studies reveal the regulatory mechanisms activated by cells during starvation to ensure that the cellular compartments involved in autophagic lipid catabolism are ready to receive, process and use these lipids. The regulators represent attractive therapeutic targets to help fight lipid-excess-associated diseases.

引用

页码：565 / 567

页数：3

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