Synthesis of 3-(4"-substituted phenyl)-5-(4′-substituted phenyl)-Δ2-pyrazolines and their derivatives

被引：0

作者：

Deshmukh, AY ^{[1
]}

Raghuwanshi, PB ^{[1
]}

Doshi, AG ^{[1
]}

机构：

[1] SSKRI Coll, Dept Chem, Washim 444105, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2002年 / 14卷 / 01期

关键词：

synthesis; substituted pyrazolines; derivatives; characterization;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

4-Substituted acetophenone (Ia-b) condenses with substituted benzaldehyde in ethanol in presence of pulverised KOH to give 4-substituted chalcone and 4'-substituted chalcone (IIa-d); (IIa-d) react with hydrazine hydrate in ethanol to give pyrazolines (IIIa-d). Pyrazolines (IIIa-d) react with acetic acid to form 1-acetyl pyrazoline (IVA-d), pyrazoline reacts with benzoyl chloride in pyridine to give 1-benzoyl pyrazoline (Va-d). Also pyrazoline reacts with sodium nitrite to give 1-nitroso pyrazoline (VIa-d). Characterisation and structural elucidation were done on the basis of chemical, analytical and spectral analysis.

引用

页码：185 / 189

页数：5

共 17 条

[1] Synthesis of isomeric Δ2-pyrazolines from 2′-hydroxy-5′-chlorochalcones and its derivatives. [J].