Clinical impact of switching conventional enzyme immunoassay with nucleic acid amplification test for suspected Clostridium difficile-associated diarrhea

被引：5

作者：

Johnson, Steven W. ^{[1
,2
,3
]}

Kanatani, Meganne ^{[4
]}

Humphries, Romney M. ^{[5
]}

Uslan, Daniel Z. ^{[6
]}

机构：

[1] Campbell Univ, Coll Pharm & Hlth Sci, Dept Pharm Practice, Buies Creek, NC 27506 USA

[2] Duke Univ, Med Ctr, Div Infect Dis, Durham, NC 27710 USA

[3] Duke Univ, Med Ctr, Dept Pharm, Durham, NC 27710 USA

[4] Univ Calif Los Angeles, Dept Pharmaceut Serv, Los Angeles, CA USA

[5] Univ Calif Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA USA

[6] Univ Calif Los Angeles, David Geffen Sch Med, Div Infect Dis, Los Angeles, CA 90095 USA

来源：

AMERICAN JOURNAL OF INFECTION CONTROL | 2013年 / 41卷 / 04期

关键词：

Toxin testing; DNA testing; Clostridium difficile infection; Stool assay;

D O I：

10.1016/j.ajic.2012.04.329

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The impact of a new Clostridium difficile nucleic acid amplification test (NAAT) on antibiotic utilization in patients with suspected C difficile infection was assessed. This single-center, cross-sectional study of 270 patients demonstrated that the use of NAAT decreased antibiotic expenditure by reducing prolonged empiric days of therapy in these patients. Copyright (C) 2013 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

引用

页码：373 / 375

页数：3

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