Asthma and asthma medication use among 4-year-old offspring of subfertile couples - association with IVF?

被引：13

作者：

Kuiper, Derk B. ^{[1
]}

Seggers, Jorien ^{[1
]}

Schendelaar, Pamela ^{[1
]}

Haadsma, Maaike L. ^{[2
]}

Roseboom, Tessa J. ^{[3
,4
]}

Heineman, Maas J. ^{[3
]}

Hadders-Algra, Mijna ^{[1
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Paediat, Div Dev Neurol, Groningen, Netherlands

[2] Univ Groningen, Univ Med Ctr Groningen, Dept Genet, Div Clin Genet, Groningen, Netherlands

[3] Univ Amsterdam, Acad Med Ctr, Dept Obstet & Gynaecol, NL-1105 AZ Amsterdam, Netherlands

[4] Univ Amsterdam, Acad Med Ctr, Dept Clin Epidemiol Biostat & Bioinformat, NL-1105 AZ Amsterdam, Netherlands

来源：

REPRODUCTIVE BIOMEDICINE ONLINE | 2015年 / 31卷 / 05期

关键词：

assisted reproductive techniques; asthma medication; asthma; in-vitro fertilization; time to pregnancy; IN-VITRO FERTILIZATION; COHORT;

D O I：

10.1016/j.rbmo.2015.08.002

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This study evaluated the prevalence of asthma and asthma medication use in 213 4-year-old singletons followed from birth onwards, including three groups of children born following: (i) controlled ovarian hyperstimulation IVF/intracytoplasmic sperm injection (ICSI); (ii) modified natural cycle IVF/ICSI; and (iii) natural conception in subfertile couples. The rate of asthma medication was higher in the ovarian hyperstimulation-IVF/ICSI than in the subfertile group (adjusted odds ratios [aOR]: 1.96 [1.00-3.84]). Time to pregnancy, a proxy for the severity of subfertility, was not associated with asthma and asthma medication. In conclusion, controlled ovarian hyperstimulation- IVF/ICSI is associated with the use of asthma medication in 4-year-old offspring of subfertile couples. (C) 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

引用

页码：711 / 714

页数：4

共 5 条

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