Static Magnetic Field Induced Hypovitaminosis D in Rat

被引：6

作者：

Aida, Lahbib ^{[1
]}

Frederic, Lecomte ^{[2
]}

Soumaya, Ghodbane ^{[1
]}

Philippe, Hubert ^{[2
]}

Mohsen, Sakly ^{[1
]}

Hafedh, Abdelmelek ^{[1
]}

机构：

[1] Carthage Univ, Lab Integrat Physiol, Fac Sci Bizerte, Jarzouna, Tunisia

[2] Univ Liege, Inst Pharm, CIRM, Lab Analyt Chem,CHU, B-4000 Liege, Belgium

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2013年 / 75卷 / 09期

关键词：

25-hydroxyvitamin D-3; calcium; field; phosphorus; rat; static magnetic; BIOAVAILABLE VITAMIN-D; METABOLISM;

D O I：

10.1292/jvms.13-0105

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

In the following study, we mainly investigate the effects of static magnetic field (SMF) (128 mT, 1 hr/day during 5 consecutive days) on 25-hydroxyvitamin D-3 and calcium homeostasis. Wistar male rats, weighing 50-70 g, were randomly divided into four experimental groups: control, SMF-exposed rat, co-exposed rats (the last day and after exposure rats received a single dose of vitamin D per os) and supplemented with vitamin D group (without exposure to SMF). Exposure to SMF induced a decrease of plasmatic 25-hydroxyvitamin D-3 level (P<0.001). While, calcium and phosphorus levels were not affected (P>0.05). The same treatment failed also to alter body, relative liver and kidney weights. Interestingly, oral supplementation with vitamin D corrected hypovitaminosis D induced by SMF. Likewise, the same treatment failed to alter calcium homeostasis. More studies are needed to evaluate how SMF induces hypovitaminosis D.

引用

页码：1181 / 1185

页数：5

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