Healing hemangiomas

被引:7
作者
Claesson-Welsh, Lena [1 ]
机构
[1] Uppsala Univ, Dept Genet & Pathol, S-75185 Uppsala, Sweden
关键词
D O I
10.1038/nm1108-1147
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Defective signaling of vascular endothelial growth factor seems to underlie the development of hemangiomas, disfiguring tumors arising early in life (pages 1236-1246).
引用
收藏
页码:1147 / 1148
页数:2
相关论文
共 12 条
  • [1] Growth characteristics of infantile hemangiomas: Implications for management
    Chang, Linda C.
    Haggstrom, Anita N.
    Drolert, Beth A.
    Baselga, Eulalia
    Chamlin, Sarah L.
    Garzon, Maria C.
    Horii, Kimberly A.
    Lucky, Anne W.
    Mancini, Anthony J.
    Metry, Denise W.
    Nopper, Amy J.
    Frieden, Ilona J.
    [J]. PEDIATRICS, 2008, 122 (02) : 360 - 367
  • [2] Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling
    Eklund, L
    Olsen, BR
    [J]. EXPERIMENTAL CELL RESEARCH, 2006, 312 (05) : 630 - 641
  • [3] Ferrara N, 2005, EXP SUPPL, V94, P209
  • [4] ROLE OF THE FLT-1 RECEPTOR TYROSINE KINASE IN REGULATING THE ASSEMBLY OF VASCULAR ENDOTHELIUM
    FONG, GH
    ROSSANT, J
    GERTSENSTEIN, M
    BREITMAN, ML
    [J]. NATURE, 1995, 376 (6535) : 66 - 70
  • [5] Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    Hiratsuka, S
    Minowa, O
    Kuno, J
    Noda, T
    Shibuya, M
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (16) : 9349 - 9354
  • [6] Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma
    Jinnin, Masatoshi
    Medici, Damian
    Park, Lucy
    Limaye, Nisha
    Liu, Yanqiu
    Boscolo, Elisa
    Bischoff, Joyce
    Vikkula, Miikka
    Boye, Eileen
    Olsen, Bjorn R.
    [J]. NATURE MEDICINE, 2008, 14 (11) : 1236 - 1246
  • [7] Mechanisms of adverse effects of anti-VEGF therapy for cancer
    Kamba, T.
    McDonald, D. M.
    [J]. BRITISH JOURNAL OF CANCER, 2007, 96 (12) : 1788 - 1795
  • [8] Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice
    Khan, Zia A.
    Boscolo, Elisa
    Picard, Arnaud
    Psutka, Sarah
    Melero-Martin, Juan M.
    Bartch, Tatianna C.
    Mulliken, John B.
    Bischoff, Joyce
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2008, 118 (07) : 2592 - 2599
  • [9] TEM8 interacts with the cleaved C5 domain of collagen α3(VI)
    Nanda, A
    Carson-Walter, EB
    Seaman, S
    Barber, TD
    Stampfl, J
    Singh, S
    Vogelstein, B
    Kinzler, KW
    St Croix, B
    [J]. CANCER RESEARCH, 2004, 64 (03) : 817 - 820
  • [10] GLUT1: A newly discovered immunohistochemical marker for juvenile hemangiomas
    North, PE
    Waner, M
    Mizeracki, A
    Mihm, MC
    [J]. HUMAN PATHOLOGY, 2000, 31 (01) : 11 - 22