Comparison of the cross-antibody response induced in sheep by inactivated bovine viral diarrhoea virus 1 and Hobi-like pestivirus

被引:22
作者
Decaro, Nicola [1 ]
Mari, Viviana [1 ]
Sciarretta, Rossana [1 ]
Lucente, Maria Stella [1 ]
Camero, Michele [1 ]
Losurdo, Michele [1 ,2 ]
Larocca, Vittorio [1 ]
Colao, Valeriana [1 ]
Cavaliere, Nicola [2 ]
Lovero, Angela [1 ]
Lorusso, Eleonora [1 ]
Buonavoglia, Canio [1 ]
机构
[1] Univ Bari, Dept Vet Med, I-70010 Bari, Italy
[2] Ist Zooprofilatt Sperimentale Puglia & Basilicata, Foggia, Italy
关键词
Hobi-like pestivirus; Bovine viral diarrhoea virus 1; Cross-antibody response; ATYPICAL PESTIVIRUS; INFECTION; CATTLE; CALVES; PIGS;
D O I
10.1016/j.rvsc.2012.11.016
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Hobi-like pestivirus, a new tentative species within genus Pestivirus, was firstly detected in foetal bovine serum batches and later associated to respiratory distress and reproductive failures in cattle. In the present study, the cross-antibody response between bovine viral diarrhoea virus 1 (BVDV-1) and the emerging pestivirus was evaluated in the sheep model. Ten sheep were immunised against BVDV-1 or Hobi-like pestivirus using inactivated preparations and the induced antibody responses were evaluated against the homologous and heterologous viruses. The results showed that heterologous antibody titres were significantly lower than the homologous ones, thus suggesting the need to develop specific vaccines against the emerging pestiviral species. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:806 / 808
页数:3
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