Zebrafish: an emerging model of vascular development and remodelling

被引:17
作者
Quaife, Nicholas M. [2 ,3 ]
Watson, Oliver [2 ,3 ]
Chico, Timothy J. A. [1 ,2 ,3 ]
机构
[1] Univ Sheffield, Lab D38, Sheffield S10 2TN, S Yorkshire, England
[2] Univ Sheffield, Dept Cardiovasc Sci, Sheffield S10 2TN, S Yorkshire, England
[3] Sheffield Teaching Hosp NHS Trust, NIHR Cardiovasc Biomed Res Unit, MRC Ctr Dev & Biomed Genet, Sheffield, S Yorkshire, England
关键词
IN-VIVO; CARDIOVASCULAR-SYSTEM; NETWORK FORMATION; CELL-FORMATION; GENE; DISRUPTION; PROMOTER; BEHAVIOR;
D O I
10.1016/j.coph.2012.06.009
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The zebrafish has attracted interest from both the scientific and general press owing to its transition from a model of developmental biology to a tool for biomedical and preclinical studies. In this brief review, we summarise the advantages of a unique model organism and outline some of its recent contributions to the understanding of vascular development and remodelling.
引用
收藏
页码:608 / 614
页数:7
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