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Surface Plasmon-Coupled Emission: What Can Directional Fluorescence Bring to the Analytical Sciences?
被引:137
作者:
Cao, Shuo-Hui
[1
]
Cai, Wei-Peng
Liu, Qian
Li, Yao-Qun
机构:
[1] Xiamen Univ, Dept Chem, Coll Chem & Chem Engn, Xiamen 361005, Peoples R China
来源:
ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 5
|
2012年
/
5卷
关键词:
optics;
plasmonics;
luminescence;
DNA;
immunoassay;
sensing;
METAL-ENHANCED FLUORESCENCE;
1ST OBSERVATION;
ENERGY-TRANSFER;
WHOLE-BLOOD;
THIN-FILMS;
SILVER NANOPARTICLES;
PLATFORM TECHNOLOGY;
DNA HYBRIDIZATION;
RESONANCE SENSORS;
SPECTROSCOPY;
D O I:
10.1146/annurev-anchem-062011-143208
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
Surface plasmon-coupled emission (SPCE) arose from the integration of fluorescence and plasmonics, two rapidly expanding research fields. SPCE is revealing novel phenomena and has potential applications in bioanalysis, medical diagnostics, drug discovery, and genomics. In SPCE, excited fluorophores couple with surface plasmons on a continuous thin metal film; plasmophores radiate into a higher-refractive index medium with a narrow angular distribution. Because of the directional emission, the sensitivity of this technique can be greatly improved with high collection efficiency. This review describes the unique features of SPCE. In particular, we focus on recent advances in SPCE-based analytical platforms and their applications in DNA sensing and the detection of other biomolecules and chemicals.
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页码:317 / 336
页数:20
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