Circadian Disruption, Sleep Loss, and Prostate Cancer Risk: A Systematic Review of Epidemiologic Studies

被引：122

作者：

Sigurdardottir, Lara G. ^{[1
,2
,3
]}

Valdimarsdottir, Unnur A. ^{[1
,2
,4
,5
,6
]}

Fall, Katja ^{[1
,4
,5
,6
]}

Rider, Jennifer R. ^{[6
,7
]}

Lockley, Steven W. ^{[8
,9
]}

Schernhammer, Eva ^{[6
,7
]}

Mucci, Lorelei A. ^{[1
,6
,7
]}

机构：

[1] Univ Iceland, Ctr Publ Hlth Sci, IS-101 Reykjavik, Iceland

[2] Univ Iceland, Fac Med, Reykjavik, Iceland

[3] Iceland Canc Soc, Reykjavik, Iceland

[4] Univ Orebro, Orebro, Sweden

[5] Orebro Univ Hosp, Clin Epidemiol Unit, Orebro, Sweden

[6] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

[7] Harvard Univ, Sch Med, Channing Lab, Boston, MA 02115 USA

[8] Brigham & Womens Hosp, Div Sleep Med, Dept Med, Boston, MA 02115 USA

[9] Harvard Univ, Div Sleep Med, Sch Med, Boston, MA 02115 USA

来源：

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION | 2012年 / 21卷 / 07期

关键词：

ROTATING-SHIFT WORKERS; BREAST-CANCER; ANTIPROLIFERATIVE ACTION; OCCUPATIONAL COHORT; MELATONIN SECRETION; VISUAL IMPAIRMENT; AIRLINE PILOTS; MT1; RECEPTOR; LNCAP CELLS; NIGHT WORK;

D O I：

10.1158/1055-9965.EPI-12-0116

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Disruption of the circadian system has been hypothesized to increase cancer risk, either because of direct disruption of the molecular machinery generating circadian rhythms or because of disruption of parameters controlled by the clock such as melatonin levels or sleep duration. This hypothesis has been studied in hormone-dependent cancers among women, but data are sparse about potential effects of circadian disruption on the risk of prostate cancer. This review systematically examines available data evaluating the effects of light at night, sleep patterns, and night shift work on prostate cancer risk. Cancer Epidemiol Biomarkers Prev; 21(7); 1002-11. (C)2012 AACR.

引用

页码：1002 / 1011

页数：10

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