Influenza A H1N1/2009 infection in pediatric solid organ transplant recipients

被引：6

作者：

Gavalda, J. ^{[1
,2
]}

Cabral, E. ^{[1
,2
]}

Alonso, E. ^{[3
]}

Perez-Romero, P. ^{[4
]}

Perez, A. ^{[4
]}

Quintero, J. ^{[5
]}

Campins, M. ^{[6
]}

Vilalta, R. ^{[7
]}

Alonso, A. ^{[8
]}

Len, O. ^{[1
,2
]}

Navarro, M. ^{[8
]}

Nieto, J. ^{[7
]}

Jara, P. ^{[3
]}

Charco, R. ^{[5
]}

Pahissa, A. ^{[1
,2
]}

Cordero, E. ^{[2
,4
]}

机构：

[1] Hosp Univ Vall dHebron, Dept Infect Dis, Barcelona 08035, Spain

[2] Spanish Network Res Infect Dis REIPI, Seville, Spain

[3] Univ Autonoma Madrid, Dept Pediat Hepatol, Hosp Univ La Paz, Madrid, Spain

[4] Hosp Univ Virgen del Rocio, Infect Dis Unit, Inst Biomed Seville IBiS, Seville, Spain

[5] Hosp Univ Vall dHebron, Dept HepatoBilioPancreat Surg & Transplants, Barcelona 08035, Spain

[6] Hosp Univ Vall dHebron, Dept Prevent Med, Barcelona 08035, Spain

[7] Hosp Univ Vall dHebron, Dept Pediat Nephrol, Barcelona 08035, Spain

[8] Hosp Univ La Paz, Dept Pediat Nephrol, Madrid, Spain

来源：

TRANSPLANT INFECTIOUS DISEASE | 2012年 / 14卷 / 06期

关键词：

influenza; H1N1; pediatric transplant; immunosuppression; H1N1; INFECTION; INVASIVE ASPERGILLOSIS; CHILDREN; VIRUS; HOSPITALIZATION; COMPLICATIONS; MORTALITY; DISEASE; RISK;

D O I：

10.1111/tid.12005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Aim and method The aim of this study was to describe the clinical characteristics and outcome of pandemic influenza A H1N1/2009 (pH1N1) infection, in a retrospective cohort of pediatric patients with kidney and/or liver transplant and confirmed pH1N1 infection from June to December 2009, diagnosed in 2 Spanish teaching hospitals. Results Forty-nine patients were included. Pneumonia was diagnosed in 4 patients (8.2%), and 3 of them required respiratory support. There were no related deaths. Conclusion Antiviral treatment within 48 h was associated with a lower likelihood of pneumonia (0/38, 0%) than treatment started after 48 h (4/11, 36.3%) (P < 0.01).

引用

页码：584 / 588

页数：5

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