A two-photon fluorescent probe for colorimetric and ratiometric monitoring of mercury in live cells and tissues

被引：95

作者：

Chen, Liyan ^{[1
]}

Park, Sang Jun ^{[2
]}

Wu, Di ^{[3
]}

Kim, Hwan Myung ^{[2
]}

Yoon, Juyoung ^{[1
]}

机构：

[1] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea

[2] Ajou Univ, Dept Chem & Energy Syst Res, Suwon, South Korea

[3] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, 122 Luoshi Rd, Wuhan 430070, Hubei, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 12期

基金：

新加坡国家研究基金会;

关键词：

AGGREGATION-INDUCED EMISSION; SELECTIVE FLUORESCENT; AQUEOUS-SOLUTION; HG2+ IONS; RECENT PROGRESS; LIVING CELLS; CHEMODOSIMETER; FRET; WATER; BENZOTHIAZOLE;

D O I：

10.1039/c8cc08608g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Owing to the extreme toxicity of mercury, methods for its selective and sensitive sensing in solutions, and in live cells and tissues are in great demand. In this study, we developed a naphthalimide-based diphenylphosphinothioyl group-containing fluorescent and colorimetric probe that selectively detects mercury (Hg2+). Upon addition of mercury (Hg2+) to a solution of the probe, both a colorimetric change from colorless to yellow and a fluorescence change from blue to green (under a 365 nm hand-held UV lamp) occur, both of which can be observed using the "naked-eye". Furthermore, the probe possesses the capability of sensing intracellular mercury in both live cells and tissues using dual-emission channels and twophoton microscopy.

引用

页码：1766 / 1769

页数：4

共 50 条

[1]

Altrichter M, 2008, AMBIO, V37, P108, DOI 10.1579/0044-7447(2008)37[108:APFCMO]2.0.CO

[2]

[3] Development and Applications of Fluorogenic Probes for Mercury(II) Based on Vinyl Ether Oxymercuration [J].

Ando, Shin ;

Koide, Kazunori .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (08) :2556-2566

[4] Aggregation-Induced Emission-Based Chemodosimeter Approach for Selective Sensing and Imaging of Hg(II) and Methylmercury Species [J].

Chatterjee, Amrita ;

Banerjee, Mainak ;

Khandare, Dipratn G. ;

Gawas, Ram U. ;

Mascarenhas, Starlaine C. ;

Ganguly, Anasuya ;

Gupta, Rishabh ;

Joshi, Hrishikesh .

ANALYTICAL CHEMISTRY, 2017, 89 (23) :12698-12704

[5] 2-Hydroxy benzothiazole modified rhodol: aggregation-induced emission and dual-channel fluorescence sensing of Hg2+ and Ag+ ions [J].

Chen, Sheng ;

Wang, Wenji ;

Yan, Mingming ;

Tu, Qin ;

Chen, Shu-Wei ;

Li, Tianbao ;

Yuan, Mao-Sen ;

Wang, Jinyi .

SENSORS AND ACTUATORS B-CHEMICAL, 2018, 255 :2086-2094

[6] A selenolactone-based fluorescent chemodosimeter to monitor mecury/methylmercury species in vitro and in vivo [J].

Chen, Xiaoqiang ;

Baek, Kyung-Hwa ;

Kim, Youngmee ;

Kim, Sung-Jin ;

Shin, Injae ;

Yoon, Juyoung .

TETRAHEDRON, 2010, 66 (23) :4016-4021

[7] Signal ratio amplification via modulation of resonance energy transfer: Proof of principle in an emission ratiometric Hg(II) sensor [J].

Coskun, Ali ;

Akkaya, Engin U. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (45) :14474-14475

[8]

Gu B, 2015, ANALYST, V140, P2778, DOI [10.1039/C5AN00273G, 10.1039/c5an00273g]

[9] Ratiometric mechanosensitive fluorescent dyes: design and applications [J].

Haidekker, Mark A. ;

Theodorakis, Emmanuel A. .

JOURNAL OF MATERIALS CHEMISTRY C, 2016, 4 (14) :2707-2718

[10] A naphthalimide-based chemodosimetric probe for ratiometric detection of hydrazine [J].

Hao, Yuanqiang ;

Zhang, Yintang ;

Ruan, Kehong ;

Chen, Wansong ;

Zhou, Binbin ;

Tan, Xiaojun ;

Wang, Yan ;

Zhao, Liqing ;

Zhang, Guan ;

Qu, Peng ;

Xu, Maotian .

SENSORS AND ACTUATORS B-CHEMICAL, 2017, 244 :417-424

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