Synthesis of Piperazine Derivatives Containing Pyridinemethyl/Thiazolemethyl and Their Biological Activities

被引：0

作者：

Li, Gang-Yue ^{[1
]}

Yan, Sheng-Gang ^{[1
]}

Jiang, Shan ^{[1
]}

Qian, Xu-Hong ^{[2
]}

Huang, Qing-Chun ^{[2
]}

Zhang, Rong ^{[3
]}

机构：

[1] Dalian Maritime Univ, Dept Mat Sci & Engn, Inst Polymer Mat, Dalian 116026, Peoples R China

[2] E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

[3] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 28卷 / 11期

关键词：

piperazine derivative; synthesis; biological activity;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

According to the principle of combination of active groups, a series of piperazine derivatives containing pyridinemethyl/thiazolemethyl were designed and synthesized from 2-chloro-5-(chloromethyl) pyridine or 2-chloro-5-(chloromethyl)thiazole via N-alkylation and addition reactions. Some compounds showed weak herbicidal activity and insecticidal activity against Aphis fabae but good insecticidal activity against Culex pipiens, among which compound 4f exhibited 100% mortality against Culex pipiens at 50 mg/L.

引用

页码：2001 / 2006

页数：6