Synthesis of Piperazine Derivatives Containing Pyridinemethyl/Thiazolemethyl and Their Biological Activities

被引：0
|
作者：
Li, Gang-Yue [1 ]
Yan, Sheng-Gang [1 ]
Jiang, Shan [1 ]
Qian, Xu-Hong [2 ]
Huang, Qing-Chun [2 ]
Zhang, Rong [3 ]
机构：
[1] Dalian Maritime Univ, Dept Mat Sci & Engn, Inst Polymer Mat, Dalian 116026, Peoples R China
[2] E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China
[3] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 28卷 / 11期
关键词：
piperazine derivative; synthesis; biological activity;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
According to the principle of combination of active groups, a series of piperazine derivatives containing pyridinemethyl/thiazolemethyl were designed and synthesized from 2-chloro-5-(chloromethyl) pyridine or 2-chloro-5-(chloromethyl)thiazole via N-alkylation and addition reactions. Some compounds showed weak herbicidal activity and insecticidal activity against Aphis fabae but good insecticidal activity against Culex pipiens, among which compound 4f exhibited 100% mortality against Culex pipiens at 50 mg/L.
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页码：2001 / 2006
页数：6
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