Sulfidation of Silver Nanoparticles: Natural Antidote to Their Toxicity

被引：351

作者：

Levard, Clement ^{[1
,2
,10
]}

Hotze, Ernest M. ^{[1
,3
]}

Colman, Benjamin P. ^{[1
,4
]}

Dale, Amy L. ^{[1
,5
]}

Truong, Lisa ^{[6
]}

Yang, X. Y. ^{[1
,4
]}

Bone, Audrey J. ^{[1
,4
]}

Brown, Gordon E., Jr. ^{[1
,2
,7
,8
]}

Tanguay, Robert L. ^{[6
]}

Di Giulio, Richard T. ^{[1
,4
]}

Bernhardt, Emily S. ^{[1
,4
]}

Meyer, Joel N. ^{[1
,4
]}

Wiesner, Mark R. ^{[1
,9
]}

Lowry, Gregory V. ^{[1
,3
]}

机构：

[1] Duke Univ, CEINT, Durham, NC 27708 USA

[2] Stanford Univ, Dept Geol & Environm Sci, Surface & Aqueous Geochem Grp, Stanford, CA 94305 USA

[3] Carnegie Mellon Univ, Dept Civil & Environm Engn, Pittsburgh, PA 15213 USA

[4] Duke Univ, Nicholas Sch Environm, Durham, NC 27708 USA

[5] Carnegie Mellon Univ, Dept Engn & Publ Policy, Pittsburgh, PA 15213 USA

[6] Oregon State Univ, Sinnhuber Aquat Res Lab, Corvallis, OR 97333 USA

[7] SLAC Natl Accelerator Lab, Stanford Synchrotron Radiat Lightsource, Menlo Pk, CA 94025 USA

[8] SLAC Natl Accelerator Lab, Dept Photon Sci, Menlo Pk, CA 94025 USA

[9] Duke Univ, Dept Civil & Environm Engn, Durham, NC 27708 USA

[10] Aix Marseille Univ, CNRS, IRD, CEREGE UM34, F-13545 Aix En Provence, France

来源：

ENVIRONMENTAL SCIENCE & TECHNOLOGY | 2013年 / 47卷 / 23期

基金：

美国国家科学基金会;

关键词：

ENVIRONMENTAL TRANSFORMATIONS; ANTIBACTERIAL ACTIVITY; AGGREGATION KINETICS; OXIDE NANOPARTICLES; ESCHERICHIA-COLI; CARBON NANOTUBES; AG NANOPARTICLES; DISSOLUTION; RELEASE; IMPACT;

D O I：

10.1021/es403527n

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Nanomaterials are highly dynamic in biological and environmental media. A critical need for advancing environmental health and safety research for nanomaterials is to identify physical and chemical transformations that affect the nanomaterial properties and their toxicity. Silver nanoparticles, one of the most toxic and well-studied nanomaterials, readily react with sulfide to form Ag(0)/Ag2S core-shell particles. Here, we show that sulfidation decreased silver nanoparticle toxicity to four diverse types of aquatic and terrestrial eukaryotic organisms (Danio rerio (zebrafish), Fundulus heteroclitus (killifish), Caenorhabditis elegans (nematode worm), and the aquatic plant Lemna minuta (least duckweed)). Toxicity reduction, which was dramatic in killifish and duckweed even for low extents of sulfidation (about 2 mol % S), is primarily associated with a decrease in Ag+ concentration after sulfidation due to the lower solubility of Ag2S relative to elemental Ag (Ag-0). These results suggest that even partial sulfidation of AgNP will decrease the toxicity of AgNPs relative to their pristine counterparts. We also show that, for a given organism, the presence of chloride in the exposure media strongly affects the toxicity results by affecting Ag speciation. These results highlight the need to consider environmental transformations of NPs in assessing their toxicity to accurately portray their potential environmental risks.

引用

页码：13440 / 13448

页数：9

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