Synthesis of optically active myo-inositol derivatives starting from phytic acid

被引:1
|
作者
Blum, C
Rehnberg, N
Spiess, B
Schlewer, G
机构
[1] CNRS, FAC PHARM, LAB PHARMACOCHIM MOL, F-67401 ILLKIRCH GRAFFENSTADEN, FRANCE
[2] PERSTORP PHARM, S-28480 PERSTORP, SWEDEN
关键词
myo-inositol; inositol phosphate; phytic acid; chiral inositol;
D O I
10.1016/S0008-6215(97)00131-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Phytic acid treated with Baker's yeast gave D-myo-inositol-1,2,6-tris(phosphate) (alpha-trinositol) which was transformed into (+)-D-1,2-O-isopropylidene-myo-inositol and (-)-D-3,4,5-tri-O-benzyl-myo-inositol, two key intermediates in the synthesis of optically active myo-inositol derivatives and related compounds. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:163 / 168
页数:6
相关论文
共 50 条
  • [31] Effect of myo-inositol(1,4,5)trisphosphate on the hydrolysis of phytic acid by phytase
    Padmanabhan, U
    Dasgupta, S
    Biswas, BB
    Dasgupta, D
    INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS, 2001, 38 (1-2): : 53 - 55
  • [32] 3-substituted myo-inositol derivatives
    Gurwitz, D
    DRUG DISCOVERY TODAY, 1999, 4 (02) : 96 - 96
  • [33] MYO-INOSITOL - ACTIVE TRANSPORT BY CRYSTALLINE LENS
    COTLIER, E
    INVESTIGATIVE OPHTHALMOLOGY, 1970, 9 (09): : 681 - +
  • [34] The maize low-phytic acid 3 encodes a myo-inositol kinase that plays a role in phytic acid biosynthesis in developing seeds
    Shi, JR
    Wang, HY
    Hazebroek, J
    Ertl, DS
    Harp, T
    PLANT JOURNAL, 2005, 42 (05): : 708 - 719
  • [35] Efficient expression of myo-inositol oxygenase in Escherichia coli and application for conversion of myo-inositol to glucuronic acid
    Zheng, Shuxiang
    Wei, Peilian
    Huang, Lei
    Cai, Jin
    Xu, Zhinan
    FOOD SCIENCE AND BIOTECHNOLOGY, 2014, 23 (02) : 445 - 450
  • [36] Efficient expression of myo-inositol oxygenase in Escherichia coli and application for conversion of myo-inositol to glucuronic acid
    Shuxiang Zheng
    Peilian Wei
    Lei Huang
    Jin Cai
    Zhinan Xu
    Food Science and Biotechnology, 2014, 23 : 445 - 450
  • [37] BIOSYNTHESIS OF L-ASCORBIC ACID FROM MYO-INOSITOL
    RAUNIO, R
    HANNINEN, O
    SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1970, 25 : 6 - &
  • [38] BIOSYNTHESIS OF L-ASCORBIC ACID FROM MYO-INOSITOL
    HANNINEN, O
    RAUNIO, R
    MARNIEMI, J
    CARBOHYDRATE RESEARCH, 1971, 16 (02) : 343 - &
  • [39] SYNTHESIS OF OPTICALLY-ACTIVE INOSITOL DERIVATIVES STARTING FROM D-GLUCURONO-6,3-LACTONE
    WATANABE, Y
    MITANI, M
    OZAKI, S
    CHEMISTRY LETTERS, 1987, (01) : 123 - 126
  • [40] Divergent syntheses of all possible optically active regioisomers of myo-inositol tris- and tetrakisphosphates
    Chung, SK
    Kwon, YU
    Shin, JH
    Chang, YT
    Lee, C
    Shin, BG
    Kim, KC
    Kim, MJ
    JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (16): : 5626 - 5637