Synthesis of optically active myo-inositol derivatives starting from phytic acid

被引:1
|
作者
Blum, C
Rehnberg, N
Spiess, B
Schlewer, G
机构
[1] CNRS, FAC PHARM, LAB PHARMACOCHIM MOL, F-67401 ILLKIRCH GRAFFENSTADEN, FRANCE
[2] PERSTORP PHARM, S-28480 PERSTORP, SWEDEN
关键词
myo-inositol; inositol phosphate; phytic acid; chiral inositol;
D O I
10.1016/S0008-6215(97)00131-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Phytic acid treated with Baker's yeast gave D-myo-inositol-1,2,6-tris(phosphate) (alpha-trinositol) which was transformed into (+)-D-1,2-O-isopropylidene-myo-inositol and (-)-D-3,4,5-tri-O-benzyl-myo-inositol, two key intermediates in the synthesis of optically active myo-inositol derivatives and related compounds. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:163 / 168
页数:6
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