Ciliary neural trophic factor: Mimicking leptin's effects in skeletal muscle?

被引：2
作者：
Dyck, DJ [1 ]
机构：
[1] Univ Guelph, Dept Human Hlth & Nutr Sci, Guelph, ON N1G 2W1, Canada
来源：
ENDOCRINOLOGY | 2006年 / 147卷 / 05期
关键词：
D O I：
10.1210/en.2006-0115
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：2075 / 2076
页数：2
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共 11 条
[1]  
BODEN G, 1996, DIABETES, V45, P3
[2]   Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance [J].
Gloaguen, I ;
Costa, P ;
Demartis, A ;
Lazzaro, D ;
DiMarco, A ;
Graziani, R ;
Paonessa, G ;
Chen, F ;
Rosenblum, CI ;
VanderPloeg, LHT ;
Cortese, R ;
Ciliberto, G ;
Laufer, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (12) :6456-6461
[3]   Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity [J].
Goodpaster, BH ;
Katsiaras, A ;
Kelley, DE .
DIABETES, 2003, 52 (09) :2191-2197
[4]   Increased protein kinase C theta in skeletal muscle of diabetic patients [J].
Itani, SI ;
Pories, WJ ;
MacDonald, KG ;
Dohm, GL .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2001, 50 (05) :553-557
[5]   Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity [J].
Lambert, PD ;
Anderson, KD ;
Sleeman, MW ;
Wong, V ;
Tan, J ;
Hijarunguru, A ;
Corcoran, TL ;
Murray, JD ;
Thabet, KE ;
Yancopoulos, GD ;
Wiegand, SJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (08) :4652-4657
[6]   Skeletal muscle triglyceride levels are inversely related to insulin action [J].
Pan, DA ;
Lillioja, S ;
Kriketos, AD ;
Milner, MR ;
Baur, LA ;
Bogardus, C ;
Jenkins, AB ;
Storlien, LH .
DIABETES, 1997, 46 (06) :983-988
[7]   Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans -: A 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents [J].
Perseghin, G ;
Scifo, P ;
De Cobelli, F ;
Pagliato, E ;
Battezzati, A ;
Arcelloni, C ;
Vanzulli, A ;
Testolin, G ;
Pozza, G ;
Del Maschio, A ;
Luzi, L .
DIABETES, 1999, 48 (08) :1600-1606
[8]   Development of leptin resistance in rat soleus muscle in response to high-fat diets [J].
Steinberg, GR ;
Dyck, DJ .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2000, 279 (06) :E1374-E1382
[9]   Overfeeding rapidly induces leptin and insulin resistance [J].
Wang, JL ;
Obici, S ;
Morgan, K ;
Barzilai, N ;
Feng, ZH ;
Rossetti, L .
DIABETES, 2001, 50 (12) :2786-2791
[10]   Ciliary neurotrophic factor prevents acute lipid-induced insulin resistance by attenuating ceramide accumulation and phosphorylation of c-Jun N-terminal kinase in peripheral tissues [J].
Watt, MJ ;
Hevener, A ;
Lancaster, GI ;
Febbraio, MA .
ENDOCRINOLOGY, 2006, 147 (05) :2077-2085
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