Vanadium-catalyzed C(sp3)-H fluorination reactions

被引：72

作者：

Xia, Ji-Bao ^{[1
]}

Ma, Yuyong ^{[1
]}

Chen, Chuo ^{[1
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Div Chem, Dept Biochem, Dallas, TX 75390 USA

来源：

ORGANIC CHEMISTRY FRONTIERS | 2014年 / 1卷 / 05期

关键词：

C-H FLUORINATION; ELECTROPHILIC FLUORINATION; METAL-FREE; UNACTIVATED ALKENES; OXIDATION; COMPLEXES; ALKANES; COPPER; HYDROXYLATION; AMINOFLUORINATION;

D O I：

10.1039/c4qo00057a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Vanadium(III) oxide catalyzes the direct fluorination of C(sp(3))-H groups with Selectfluor. This reaction is operationally simple. The catalyst and the reaction by-product can be removed easily by filtration. Using this method, a fluorine atom can be introduced to the tertiary position of 1,4-cineole and L-menthone selectively.

引用

页码：468 / 472

页数：5

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