Highly Efficient Synthesis of Arylpyrrole Derivatives via Rh(III)-Catalyzed Direct C-H Arylation with Aryl Boronic Acids

被引：13

作者：

Wang, Liang ^{[1
,2
]}

Li, Zhan ^{[1
]}

Qu, Xing ^{[1
]}

Peng, Wangming ^{[1
]}

机构：

[1] Jianghan Univ, Key Lab Optoelect Chem Mat & Devices, Minist Educ, Wuhan 430056, Hunan, Peoples R China

[2] Jianghan Univ, Sch Chem & Envirom Engn, Wuhan 430056, Hunan, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2015年 / 33卷 / 09期

基金：

中国国家自然科学基金;

关键词：

rhodium-catalysis; C-H arylation; arylpyrrole derivatives; aryl boronic acids; ONE-POT SYNTHESIS; N BOND FORMATION; SUBSTITUTED PYRROLES; CATALYZED ARYLATION; PALLADIUM; FUNCTIONALIZATION; INDOLES; HETEROCYCLES; LAMELLARINS; ANNULATION;

D O I：

10.1002/cjoc.201500354

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and facile method for synthesis of 2-arylpyrroles through Rh(III)-catalyzed direct C-H arylation with pyrrole derivatives and aryl boronic acids has been developed. This reaction could proceed under mild reaction conditions and afford a series of 2-arylated products in good to excellent yields. The gram-scale experiment has been conducted to demonstrate the synthetic potential of this methodology.

引用

页码：1015 / 1018

页数：4

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