Highly enantioselective hetero Diels-Alder reactions of N-sulfinyl dienophiles promoted by copper(II)- and zinc(II)-chiral bis(oxazoline) complexes

被引：17

作者：

Bayer, A

Gautun, OR ^{[1
]}

机构：

[1] Norwegian Univ Sci & Technol, Dept Chem, NO-7491 Trondheim, Norway

[2] Univ Tromso, Dept Chem, NO-9037 Tromso, Norway

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 21期

关键词：

D O I：

10.1016/S0957-4166(01)00525-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Hetero Diels-Alder reactions of 1,3-cyclohexadiene with N-sulfinyl dienophiles 1a or 1b, promoted by Cu(II)- or Zn(II)-chiral bis(oxazoline) complexes, afforded endo adducts in high yields (up to 85%) and enantiomeric excess (e.e. of up to >98%) under stoichiometric conditions. With 10 mol% loading of the Zn(II) catalyst up to 75% e.e. was obtained for the endo adduct (endo:exo=10:1, total yield 68%). (C) 2002 Elsevier Science Ltd. All rights reserved.

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页码：2937 / 2939

页数：3

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