Hydrogenation of N-Acylcarbamates and N-Acylsulfonamides Catalyzed by a Bifunctional [Cp*Ru(PN)] Complex

被引：65

作者：

Ito, Masato ^{[1
]}

Koo, Lee Wei ^{[1
]}

Himizu, Akio ^{[1
]}

Kobayashi, Chika ^{[1
]}

Sakaguchi, Ayaka ^{[1
]}

Ikariya, Takao ^{[1
]}

机构：

[1] Tokyo Inst Technol, Grad Sch Sci & Engn, Dept Appl Chem, Meguro Ku, Tokyo 1528552, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 07期

关键词：

alcohols; enantioselectivity; hydrogenation; ligand effects; ruthenium; ASYMMETRIC TRANSFER HYDROGENATION; STEREOSELECTIVE HYDROGENATION; MOLECULAR CATALYSTS; REDUCTIVE CLEAVAGE; KETONES; ALCOHOLS; DIHYDROGEN; MECHANISM; HYDROGENOLYSIS; BEARING;

D O I：

10.1002/anie.200805307

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Awakening of the Cp one: the bifunctional complex 1 facilitates the interaction with substrates bearing less electrophilic carbon atoms than ketones, epoxides, and imides. The title reaction was applicable to the reduction of Evans' asymmetric alkylation products to the chiral alcohols along with gtood recovery of the chiral oxazolidinone auxiliary. EWG=electron- withdrawing group. © 2009 Wiley-VCH Verleg GmbH & Co. KGaA.

引用

页码：1324 / 1327

页数：4

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