Necrobiosis Lipoidica

被引：63

作者：

Sibbald, Cathryn ^{[1
]}

Reid, Sophia ^{[2
]}

Alavi, Afsaneh ^{[1
]}

机构：

[1] Univ Toronto, Dept Med Dermatol, Toronto, ON, Canada

[2] Univ Calif Irvine, Dept Med, Irvine, CA 92717 USA

来源：

DERMATOLOGIC CLINICS | 2015年 / 33卷 / 03期

关键词：

Necrobiosis lipoidica; Ulcerations; Necrobiosis lipoidica/diagnosis; Necrobiosis lipoidica/therapy; FUMARIC-ACID ESTERS; GRANULOMA-ANNULARE; INTRAVENOUS IMMUNOGLOBULIN; VENOUS INSUFFICIENCY; TOPICAL TACROLIMUS; DIABETICORUM; INFLIXIMAB; COLLAGEN; PATIENT; THERAPY;

D O I：

10.1016/j.det.2015.03.003

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Necrobiosis lipoidica is a granulomatous condition presenting as indolent atrophic plaques, often on the lower extremities. There is a multitude of case reports suggesting possible associations and documenting different therapeutic alternatives with varied success. Important complications include ulceration and the development of squamous cell carcinoma. The disease course is often indolent and recurrent despite treatment. This article reviews the etiopathogenesis, clinical presentations, and evidence for treatment alternatives of this condition.

引用

页码：343 / +

页数：19

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