Transition-Metal Free Construction of Isoquinoline-fused Triazines Containing Alkenyl C-X Bonds

被引：51

作者：

Cheng, Xiao ^{[1
,2
]}

Cao, Xia ^{[1
,2
]}

Zhou, Shuang-Jing ^{[1
,2
]}

Cai, Bao-Gui ^{[1
,2
]}

He, Xiang-Kui ^{[1
,2
]}

Xuan, Jun ^{[1
,2
,3
]}

机构：

[1] Anhui Univ, Dept Chem, Hefei 230601, Anhui, Peoples R China

[2] Anhui Univ, Anhui Prov Key Lab Chem Inorgan Organ Hybrid Func, Hefei 230601, Anhui, Peoples R China

[3] Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Anhui, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2019年 / 361卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Transition-metal free; Isoquinoline-fused Triazines'; azaoxyallyl cations; C; N-cyclic azomethine imines; heterocyclic compounds; C; N-CYCLIC AZOMETHINE IMINES; FORMED AZAOXYALLYL CATIONS; AZA-OXYALLYL CATIONS; 3+3 CYCLOADDITION; 1,3-DIPOLAR CYCLOADDITION; ACCESS; CYCLIZATION; ANNULATION; CHEMISTRY; HETEROCYCLES;

D O I：

10.1002/adsc.201801181

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A halogen and base-mediated [3+3]-cycloaddition reaction of in situ generated azaoxyallyl cations with in situ formed C,N-cyclic azomethine imines is reported. This one-pot transition metal-free cycloaddition process exhibits broad substrate scope, excellent functional group tolerance, and affords a series of biologically important isoquinoline-fused triazines in good to excellent yields, which containing valuable alkenyl C-X bonds (X-Br, I).

引用

页码：1230 / 1235

页数：6

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