Transition-Metal Free Construction of Isoquinoline-fused Triazines Containing Alkenyl C-X Bonds

被引：51
作者：
Cheng, Xiao [1 ,2 ]
Cao, Xia [1 ,2 ]
Zhou, Shuang-Jing [1 ,2 ]
Cai, Bao-Gui [1 ,2 ]
He, Xiang-Kui [1 ,2 ]
Xuan, Jun [1 ,2 ,3 ]
机构：
[1] Anhui Univ, Dept Chem, Hefei 230601, Anhui, Peoples R China
[2] Anhui Univ, Anhui Prov Key Lab Chem Inorgan Organ Hybrid Func, Hefei 230601, Anhui, Peoples R China
[3] Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Anhui, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2019年 / 361卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Transition-metal free; Isoquinoline-fused Triazines'; azaoxyallyl cations; C; N-cyclic azomethine imines; heterocyclic compounds; C; N-CYCLIC AZOMETHINE IMINES; FORMED AZAOXYALLYL CATIONS; AZA-OXYALLYL CATIONS; 3+3 CYCLOADDITION; 1,3-DIPOLAR CYCLOADDITION; ACCESS; CYCLIZATION; ANNULATION; CHEMISTRY; HETEROCYCLES;
D O I：
10.1002/adsc.201801181
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A halogen and base-mediated [3+3]-cycloaddition reaction of in situ generated azaoxyallyl cations with in situ formed C,N-cyclic azomethine imines is reported. This one-pot transition metal-free cycloaddition process exhibits broad substrate scope, excellent functional group tolerance, and affords a series of biologically important isoquinoline-fused triazines in good to excellent yields, which containing valuable alkenyl C-X bonds (X-Br, I).
引用
收藏
页码：1230 / 1235
页数：6
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