Background Limited data exist regarding reconstructive outcomes in patients with head and neck sarcoma. Methods A review of patients with head and neck sarcoma who underwent oncologic resection and microvascular free flap reconstruction between 2001 and 2010 was performed. Results In all, 133 patients were included in the study. The overall rate of perioperative complications was 30.1%, including a flap loss rate of 3.0%. The rate of late recipient site complications was 7.5% and occurred more frequently with postoperative radiation (19.0%) compared with preoperative radiation, prior radiation, and no radiation (5.3%, 3.0%, and 0%, respectively; p = .005). Most patients achieved intelligible speech (88.3%) and feeding tube independence (94.4%). Conclusions Good reconstructive outcomes can be attained in patients with head and neck sarcoma undergoing resection and free flap reconstruction. Preoperative radiation may be preferable to postoperative radiation in select cases due to fewer long-term complications without an increased rate of complications or flap loss. (c) 2012 Wiley Periodicals, Inc. Head Neck, 2013
机构:
Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Kim, Joseph K.
Verma, Nipun
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Verma, Nipun
McBride, Sean
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
McBride, Sean
Riaz, Nadeem
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Riaz, Nadeem
Boyle, Jay O.
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Mem Sloan Kettering Canc Ctr, Dept Surg, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Boyle, Jay O.
Spielsinger, Daniel
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Spielsinger, Daniel
Sabol, Christopher
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Sabol, Christopher
Waldenberg, Todd
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Waldenberg, Todd
Brinkman, Thomas
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Brinkman, Thomas
Alektiar, Kaled
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Alektiar, Kaled
Lee, Nancy Y.
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
Lee, Nancy Y.
Tsai, C. Jillian
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1250 First Ave, New York, NY 10065 USA
机构:
Univ Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, CanadaUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada
Hahn, Ezra
Huang, Shao Hui
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Univ Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, CanadaUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada
Huang, Shao Hui
Hosni, Ali
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Univ Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, CanadaUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada
Hosni, Ali
Razak, Albiruni Abdul
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Univ Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Div Med Oncol, Toronto, ON, CanadaUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada
Razak, Albiruni Abdul
Jones, Robin L.
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Royal Marsden Hosp, Inst Canc Res, London, EnglandUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada
Jones, Robin L.
Dickson, Brendan C.
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Sinai Hlth Syst, Dept Pathol & Lab Med, Toronto, ON, CanadaUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada
Dickson, Brendan C.
Sturgis, Erich M.
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Univ Texas MD Anderson Canc Ctr, Dept Head & Neck Surg, Houston, TX 77030 USAUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada
Sturgis, Erich M.
Patel, Snehal G.
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Mem Sloan Kettering Canc Ctr, Dept Surg, 1275 York Ave, New York, NY 10021 USAUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada
Patel, Snehal G.
O'Sullivan, Brian
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Univ Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, CanadaUniv Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Dept Radiat Oncol, Toronto, ON, Canada