On the Lubensky-Nelson Model of Polymer Translocation through Nanopores

被引：9

作者：

Reimann, Peter ^{[1
]}

Meyer, Andreas ^{[1
]}

Getfert, Sebastian ^{[1
]}

机构：

[1] Univ Bielefeld, Fak Phys, Bielefeld, Germany

来源：

BIOPHYSICAL JOURNAL | 2012年 / 103卷 / 05期

关键词：

DNA TRANSLOCATION; MEMBRANE CHANNEL; ORIENTATION DISCRIMINATION; POLYNUCLEOTIDE MOLECULES; RNA MOLECULES; TRANSPORT; DYNAMICS; PORE; HETEROGENEITY; HOMOPOLYMERS;

D O I：

10.1016/j.bpj.2012.07.036

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We revisit the one-dimensional stochastic model of an earlier study by D. K. Lubensky and D. R. Nelson for the electrically driven translocation of polynucleotides through alpha-hemolysin pores. We show that the model correctly describes two further important properties of the experimentally observed translocation time distributions, namely their spread (width) and their exponential The resulting overall agreement between theoretical and experimental translocation time distributions is thus very good.

引用

页码：889 / 897

页数：9

共 45 条

[1] Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules [J].