Nanotechnology for the development of new cosmetic formulations

被引:108
作者
Santos, Ana Claudia [1 ,2 ]
Morais, Francisca [1 ]
Simoes, Ana [1 ,2 ]
Pereira, Irina [1 ,2 ]
Sequeira, Joana A. D. [1 ]
Pereira-Silva, Miguel [1 ]
Veiga, Francisco [1 ,2 ]
Ribeiro, Antonio [1 ,3 ]
机构
[1] Univ Coimbra, Dept Pharmaceut Technol, Fac Pharm, Coimbra, Portugal
[2] Univ Coimbra, Grp Pharmaceut Technol, REQUIMTE LAQV, Fac Pharm, Coimbra, Portugal
[3] Inst Mol & Cell Biol, Grp Genet Cognit Dysfunct, i3S, Porto, Portugal
关键词
Cosmetic; nanocosmetic; nanoparticle; nanotechnology; regulatory; toxicology; TOPICAL DRUG-DELIVERY; MEDIATED GOLD NANOPARTICLES; SOLID LIPID NANOPARTICLES; ZINC-OXIDE NANOPARTICLES; TRANSDERMAL DELIVERY; TITANIUM-DIOXIDE; SKIN DELIVERY; STATISTICAL OPTIMIZATION; POLYMERIC NANOPARTICLES; MOISTURE RETENTION;
D O I
10.1080/17425247.2019.1585426
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Introduction: Nanotechnology is an increasingly widespread area of research for its various applications and advantages. Accordingly, nanotechnology has been the focus of investment in different areas of science, namely as a technological strategy for the development of cosmetics formulations. Nanosystems allow for a profit skin penetration and an effective release profile of ingredients, which contributes to superior technological and cosmetic effects. The applications of nanocosmetics are numerous, from anti-aging care, make-up, nails, deodorants, oral care, sunscreens, and hair care. However, as an area of emerging knowledge, it has now begun to encourage investigations into its toxicology profile, particularly regarding health damage and environmental pollution. Also, the regulatory area saw its adaptation concerning the use of formulations containing nanotechnology.Areas covered: A description of the nanosystems so far applied in the development of cosmetics is presented. Moreover, an outline concerning lipid-based-nanosystems, polymeric-based nanoparticles, metal-based nanoparticles, silica nanoparticles, and additional nanosystems (dendrimers, nanocrystals, fullerenes, nanodiamonds, and cyclodextrins) towards the obtainment of effective cosmetic outcomes is addressed. The concerning toxicological as well as the regulatory aspects are also discussed.Expert opinion: This innovative and timely review emphasizes that nanosystems constitute a highly promising technology strategy towards the obtainment of superior and ground-breaking cosmetic formulations.
引用
收藏
页码:313 / 330
页数:18
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