Microfluidics and photonics for Bio-System-on-a-Chip: A review of advancements in technology towards a microfluidic flow cytometry chip

被引：130
作者：
Godin, Jessica [1 ]
Chen, Chun-Hao [1 ]
Cho, Sung Hwan [1 ]
Qiao, Wen [2 ]
Tsai, Frank [1 ]
Lo, Yu-Hwa [1 ]
机构：
[1] Univ Calif San Diego, Dept Elect & Comp Engn, La Jolla, CA 92093 USA
[2] Zhejiang Univ, State Key Lab, Natl Engn Res Ctr Opt Instrument, Hangzhou, Zhejiang, Peoples R China
来源：
JOURNAL OF BIOPHOTONICS | 2008年 / 1卷 / 05期
关键词：
Biomedical instrumentation and transducers; including micro-electro-mechanical systems (MEMS); cells on a chip; other integrated-optical elements and systems; fabrication techniques; lithography; pattern transfer; flows in micro-electromechanical systems (MEMS) and nanoelectromechanical systems (NEMS); fluorescence;
D O I：
10.1002/jbio.200810018
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Microfluidics and photonics come together to form a field commonly referred to as 'optofluidics'. Flow cytometry provides the field with a technology base from which both microfluidic and photonic components be developed and integrated into a useful device. This article reviews some of the more recent developments to familiarize a reader with the current state of the technologies and also highlights the requirements of the device and how researchers are working to meet these needs A microfluidic flow cytometer prototype employing on-chip lenses for illumination and light collection in conjunction with a microfluidic sample flow system for device miniaturization.
引用
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页码：355 / 376
页数：22
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