Microfluidics and photonics for Bio-System-on-a-Chip: A review of advancements in technology towards a microfluidic flow cytometry chip

被引：131

作者：

Godin, Jessica ^{[1
]}

Chen, Chun-Hao ^{[1
]}

Cho, Sung Hwan ^{[1
]}

Qiao, Wen ^{[2
]}

Tsai, Frank ^{[1
]}

Lo, Yu-Hwa ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Elect & Comp Engn, La Jolla, CA 92093 USA

[2] Zhejiang Univ, State Key Lab, Natl Engn Res Ctr Opt Instrument, Hangzhou, Zhejiang, Peoples R China

来源：

JOURNAL OF BIOPHOTONICS | 2008年 / 1卷 / 05期

关键词：

Biomedical instrumentation and transducers; including micro-electro-mechanical systems (MEMS); cells on a chip; other integrated-optical elements and systems; fabrication techniques; lithography; pattern transfer; flows in micro-electromechanical systems (MEMS) and nanoelectromechanical systems (NEMS); fluorescence;

D O I：

10.1002/jbio.200810018

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Microfluidics and photonics come together to form a field commonly referred to as 'optofluidics'. Flow cytometry provides the field with a technology base from which both microfluidic and photonic components be developed and integrated into a useful device. This article reviews some of the more recent developments to familiarize a reader with the current state of the technologies and also highlights the requirements of the device and how researchers are working to meet these needs A microfluidic flow cytometer prototype employing on-chip lenses for illumination and light collection in conjunction with a microfluidic sample flow system for device miniaturization.

引用

页码：355 / 376

页数：22

共 111 条

[11] Rapid fabrication of a microfluidic device with integrated optical waveguides for DNA fragment analysis [J].

Bliss, Christopher L. ;

McMullin, James N. ;

Backhouse, Christopher J. .

LAB ON A CHIP, 2007, 7 (10) :1280-1287

[12] Continuous separation of cells by balanced dielectrophoretic forces at multiple frequencies [J].

Braschler, Thomas ;

Demierre, Nicolas ;

Nascimento, Elisabete ;

Silva, Tiago ;

Oliva, Abel G. ;

Renaud, Philippe .

LAB ON A CHIP, 2008, 8 (02) :280-286

[13] PDMS 2D optical lens integrated with microfluidic channels: principle and characterization [J].

Camou, S ;

Fujita, H ;

Fujii, T .

LAB ON A CHIP, 2003, 3 (01) :40-45

[14] An integrated fluorescence detection system in poly(dimethylsiloxane) for microfluidic applications [J].

Chabinyc, ML ;

Chiu, DT ;

McDonald, JC ;

Stroock, AD ;

Christian, JF ;

Karger, AM ;

Whitesides, GM .

ANALYTICAL CHEMISTRY, 2001, 73 (18) :4491-4498

[15]

CHANG CC, 2007, J MICROMECHANICS MIC, V17

[16] Shape-controlled, high fill-factor microlens arrays fabricated by a 3D diffuser lithography and plastic replication method [J].

Chang, SI ;

Yoon, JB .

OPTICS EXPRESS, 2004, 12 (25) :6366-6371

[17]

CHANG SI, 2005, 18 ANN M IEEE LAS EL, P749

[18]

CHEN CH, 2008, HIGH SPEED HYDRODYNA

[19] Topologic mixing on a microfluidic chip [J].

Chen, H ;

Meiners, JC .

APPLIED PHYSICS LETTERS, 2004, 84 (12) :2193-2195

[20] Lab-on-a-chip devices for global health: Past studies and future opportunities [J].

Chin, Curtis D. ;

Linder, Vincent ;

Sia, Samuel K. .

LAB ON A CHIP, 2007, 7 (01) :41-57

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