Gas Chromatographic Determination of Prostaglandins

被引:18
作者
Baranowski, R. [1 ]
Pacha, K. [1 ]
机构
[1] Silesian Tech Univ, Dept Analyt & Gen Chem, PL-44100 Gliwice, Poland
关键词
Prostaglandins; Sample preparation; Derivatization; Biological samples; Gas chromatography;
D O I
10.2174/1389557024605465
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Progress in separation and detection of prostaglandins and the other metabolites of arachidonic acid by means of GC-ECD, GC-MS, and GC-MS-MS in the course of the past fifteen years was reviewed. One discussed the problems of sample preparation, selection of proper chromatographic conditions, and detection modes available. Finally, applications of the methods developed to detection and quantification of prostanoids in biological material was presented.
引用
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页码:135 / 144
页数:10
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