Gas Chromatographic Determination of Prostaglandins

被引：18

作者：

Baranowski, R. ^{[1
]}

Pacha, K. ^{[1
]}

机构：

[1] Silesian Tech Univ, Dept Analyt & Gen Chem, PL-44100 Gliwice, Poland

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2002年 / 2卷 / 02期

关键词：

Prostaglandins; Sample preparation; Derivatization; Biological samples; Gas chromatography;

D O I：

10.2174/1389557024605465

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Progress in separation and detection of prostaglandins and the other metabolites of arachidonic acid by means of GC-ECD, GC-MS, and GC-MS-MS in the course of the past fifteen years was reviewed. One discussed the problems of sample preparation, selection of proper chromatographic conditions, and detection modes available. Finally, applications of the methods developed to detection and quantification of prostanoids in biological material was presented.

引用

页码：135 / 144

页数：10

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