A new strategy for statistical analysis-based fingerprint establishment: Application to quality assessment of Semen sojae praeparatum

被引：40

作者：

Guo, Hui ^{[1
,2
]}

Zhang, Zhen ^{[1
,2
]}

Yao, Yuan ^{[1
,2
,3
]}

Liu, Jialin ^{[1
,2
]}

Chang, Ruirui ^{[1
,2
,3
]}

Liu, Zhao ^{[4
]}

Hao, Hongyuan ^{[4
]}

Huang, Taohong ^{[4
]}

Wen, Jun ^{[1
,2
]}

Zhou, Tingting ^{[1
,2
]}

机构：

[1] Second Mil Med Univ, Sch Pharm, Shanghai 200433, Peoples R China

[2] Second Mil Med Univ, Shanghai Key Lab Pharmaceut Metabolite Res, Sch Pharm, Shanghai 200433, Peoples R China

[3] Anhui Univ Chinese Med, Sch Pharm, Hefei 230031, Anhui, Peoples R China

[4] Shimadzu China Co Ltd, Shanghai 200233, Peoples R China

来源：

FOOD CHEMISTRY | 2018年 / 258卷

关键词：

Semen sojae praeparatum; SA; HCA; PCA; Fingerprint; Quality control; ANTIOXIDANT ACTIVITIES; MASS-SPECTROMETRY; SOY; HPLC; AUTHENTICATION; IDENTIFICATION; ISOFLAVONES; PRODUCTS; CANCER; DAD;

D O I：

10.1016/j.foodchem.2018.03.067

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Semen sojae praeparatum with homology of medicine and food is a famous traditional Chinese medicine. A simple and effective quality fingerprint analysis, coupled with chemometrics methods, was developed for quality assessment of Semen sojae praeparatum. First, similarity analysis (SA) and hierarchical clusting analysis (HCA) were applied to select the qualitative markers, which obviously influence the quality of Semen sojae praeparatum. 21 chemicals were selected and characterized by high resolution ion trap/time-of-flight mass spectrometry (LCIT-TOF-MS). Subsequently, principal components analysis (PCA) and orthogonal partial least squares discriminant analysis (OPLS-DA) were conducted to select the quantitative markers of Semen sojae praeparatum samples from different origins. Moreover, 11 compounds with statistical significance were determined quantitatively, which provided an accurate and informative data for quality evaluation. This study proposes a new strategy for "statistic analysis-based fingerprint establishment", which would be a valuable reference for further study.

引用

页码：189 / 198

页数：10

共 28 条

[1]

[Anonymous], 2004, GUID IND BOT DRUG PR

[2] Contents variation analysis of free amino acids, nucleosides and nucleobases in semen sojae praeparatum fermentation using UFLC-QTRAP MS [J].

Chai, Chuan ;

Cui, Xiaobing ;

Shan, Chenxiao ;

Yu, Sheng ;

Wen, Hongmei .

BIOMEDICAL CHROMATOGRAPHY, 2017, 31 (11)

[3] Chemical fingerprinting of Gardenia jasminoides Ellis by HPLC-DAD-ESI-MS combined with chemometrics methods [J].

Han, Yan ;

Wen, Jun ;

Zhou, Tingting ;

Fan, Guorong .

FOOD CHEMISTRY, 2015, 188 :648-657

[4] Multi-response optimisation of the extraction solvent system for phenolics and antioxidant activities from fermented soy flour using a simplex-centroid design [J].

Handa, Cintia Ladeira ;

de Lima, Fernando Sanches ;

Geton Guelfi, Marcela Fernanda ;

Georgetti, Sandra Regina ;

Ida, Elza Iouko .

FOOD CHEMISTRY, 2016, 197 :175-184

[5] Functional Characterization of Bacterial Communities Responsible for Fermentation of Doenjang: A Traditional Korean Fermented Soybean Paste [J].

Jung, Woo Yong ;

Jung, Ji Young ;

Lee, Hyo Jung ;

Jeon, Che Ok .

FRONTIERS IN MICROBIOLOGY, 2016, 7

[6] Metabolome based volatiles profiling in 13 date palm fruit varieties from Egypt via SPME GC-MS and chemometrics [J].

Khalil, Mohammed N. A. ;

Fekry, Mostafa I. ;

Farag, Mohamed A. .

FOOD CHEMISTRY, 2017, 217 :171-181

[7] Dietary phytoestrogens [J].

Kurzer, MS ;

Xu, X .

ANNUAL REVIEW OF NUTRITION, 1997, 17 :353-381

[8] High resolution LC-ESI-TOF-mass spectrometry method for fast separation, identification, and quantification of 12 isoflavones in soybeans and soybean products [J].

Lee, Mi Jin ;

Chung, Ill-Min ;

Kim, Hunjung ;

Jung, Mun Yhung .

FOOD CHEMISTRY, 2015, 176 :254-262

[9]

Lee MM, 2003, CANCER EPIDEM BIOMAR, V12, P665

[10] Comparative evaluation of microbial diversity and metabolite profiles in doenjang, a fermented soybean paste, during the two different industrial manufacturing processes [J].

Lee, Sunmin ;

Lee, Sarah ;

Singh, Digar ;

Oh, Ji Young ;

Jeon, Eun Jung ;

Ryu, Hyung Seok ;

Lee, Dong Wan ;

Kim, Beom Seok ;

Lee, Choong Hwan .

FOOD CHEMISTRY, 2017, 221 :1578-1586

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