In fierce market competition, how to improve business management level is a key factor for an enterprise to survive and to keep maintenance development. The paper describes principles and specific steps of the implementation of target cost management at first. Then, with applying of target cost management in real estate development project, the article discovered some problems existing in cost management of real estate development project, such as lack of cost management consciousness, inappropriate incentives, and etc. In order to solve the problems and strengthen cost management of real estate development project, the paper puts forward solutions, such as applying target cost management in whole process of cost control system and so on, to enhance core competitiveness of real estate development project.