Electrochemical Behavior and Voltammetric Determination of Diclofenac at a Multi-Walled Carbon Nanotube-Ionic Liquid Composite Modified Carbon Ceramic Electrode

被引：21
作者：
Razmi, Habib [1 ]
Sarhang-Zadeh, Kianoush [1 ]
Mohammad-Rezaei, Rahim [1 ]
机构：
[1] Azarbaijan Shahid Madani Univ, Electroanalyt Chem Res Lab, Fac Sci, Tabriz, Iran
来源：
ANALYTICAL LETTERS | 2013年 / 46卷 / 12期
关键词：
Carbon nanotube; Diclofenac; Ionic liquid; Modified electrode; CONTROLLED-RELEASE INDOMETHACIN; PYROLYTIC-GRAPHITE ELECTRODE; CONTROLLED CLINICAL-TRIAL; PHARMACEUTICAL FORMULATION; PASTE ELECTRODE; SODIUM; OXIDATION; CHROMATOGRAPHY; CYCLODEXTRIN; URINE;
D O I：
10.1080/00032719.2013.777919
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
This work describes the electrochemical behavior of diclofenac on the surface of a carbonceramic electrode (CCE) modified with multi-walled carbon nanotubes (MWCNT) and an ionic liquid (IL) composite. The MWCNT-IL composite showed an enhancement effect in the electro-oxidation of diclofenac with respect to a bare carbon ceramic electrode. Based on the experimental outcomes, a possible mechanism for the electro-oxidation of diclofenac is proposed and discussed. Under the optimized experimental conditions, the MWCNT-IL CCE showed a linear response to diclofenac over the concentration range 50nM-20 mu M with a detection limit of 27nM. The developed diclofenac sensor showed good stability, sensitivity, and reproducibility in the measurement of diclofenac in human blood plasma samples.
引用
收藏
页码：1885 / 1896
页数：12
相关论文
共 27 条
[1]   Spectrofluorimetric determination of diclofenac in the presence of α-cyclodextrin [J].
Arancibia, JA ;
Boldrini, MA ;
Escandar, GM .
TALANTA, 2000, 52 (02) :261-268
[2]   Multi-walled carbon nanotubes/chitosan polymer composite modified glassy carbon electrode for sensitive simultaneous determination of levodopa and morphine [J].
Babaei, Ali ;
Babazadeh, Mitra .
ANALYTICAL METHODS, 2011, 3 (10) :2400-2405
[3]   SPECTROPHOTOMETRIC DETERMINATION OF DICLOFENAC SODIUM WITH METHYLENE-BLUE [J].
BOTELLO, JC ;
PEREZCABALLERO, G .
TALANTA, 1995, 42 (01) :105-108
[4]   Voltammetric Determination of Diclofenac Sodium Using Tyrosine-Modified Carbon Paste Electrode [J].
Chethana, B. K. ;
Basavanna, S. ;
Naik, Y. Arthoba .
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2012, 51 (31) :10287-10295
[5]   CONTROLLED-RELEASE INDOMETHACIN AND SUSTAINED-RELEASE DICLOFENAC SODIUM IN THE TREATMENT OF RHEUMATOID-ARTHRITIS - A COMPARATIVE CONTROLLED CLINICAL-TRIAL [J].
CROWLEY, B ;
HAMILL, JJ ;
LYNDON, S ;
MCKELLICAN, JF ;
WILLIAMS, P ;
MILLER, AJ .
CURRENT MEDICAL RESEARCH AND OPINION, 1990, 12 (03) :143-150
[6]   PROSTAGLANDINS, ASPIRIN-LIKE DRUGS AND ANALGESIA [J].
FERREIRA, SH .
NATURE-NEW BIOLOGY, 1972, 240 (102) :200-&
[7]   Determination of cyanocobalamin, betamethasone, and diclofenac sodium in pharmaceutical formulations, by high performance liquid chromatography [J].
González, L ;
Yuln, G ;
Volonté, MG .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1999, 20 (03) :487-492
[8]   CONTROLLED-RELEASE INDOMETHACIN AND SUSTAINED-RELEASE DICLOFENAC SODIUM IN THE TREATMENT OF OSTEOARTHRITIS - A COMPARATIVE CONTROLLED CLINICAL-TRIAL IN GENERAL-PRACTICE [J].
GOSTICK, N ;
JAMES, IGV ;
KHONG, TK ;
ROY, P ;
SHEPHERD, PR ;
MILLER, AJ .
CURRENT MEDICAL RESEARCH AND OPINION, 1990, 12 (03) :135-142
[9]   The effect of modifying an edge-plane pyrolytic graphite electrode with single-wall carbon nanotubes on its use for sensing diclofenac [J].
Goyal, Rajendra N. ;
Chatterjee, Sanghamitra ;
Rana, Anoop Raj Singh .
CARBON, 2010, 48 (14) :4136-4144
[10]   Electrochemical investigations of diclofenac at edge plane pyrolytic graphite electrode and its determination in human urine [J].
Goyal, Rajendra N. ;
Chatterjee, Sanghamitra ;
Agrawal, Bharati .
SENSORS AND ACTUATORS B-CHEMICAL, 2010, 145 (02) :743-748
123