Off-label indications for topical tacrolimus

被引：8

作者：

Hengge, U. R. ^{[1
]}

机构：

[1] Hautzentrum Prof Hengge, D-40210 Dusseldorf, Germany

来源：

HAUTARZT | 2013年 / 64卷 / 10期

关键词：

Vitiligo; Seborrheic dermatitis; Perioral dermatitis; Rosacea; Lichen sclerosus et atrophicus; LICHEN-SCLEROSUS; 0.1-PERCENT TACROLIMUS; CHILDHOOD VITILIGO; OINTMENT; DERMATITIS; ROSACEA; TRIAL; CLOBETASOL; SAFETY;

D O I：

10.1007/s00105-013-2594-1

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The topical calcineurin antagonist tacrolimus plays an important role in the treatment of different forms of eczema because of its favorable risk profile. In addition, different off-label indications have been clinically tested where tacrolimus ointment has achieved clinical improvement. This article discusses off-label treatment of vitiligo, seborrheic dermatitis, steroid rosacea, perioral dermatitis, rosacea and lichen sclerosus.

引用

页码：752 / 756

页数：5

共 19 条

[1] Tacrolimus effect on rosacea [J].

Bamford, JTM ;

Elliott, BA ;

Haller, IV .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2004, 50 (01) :107-108

[2] Tacrolimus 0•1% ointment for seborrhoeic dermatitis:: an open-label pilot study [J].

Braza, TJ ;

DiCarlo, JB ;

Soon, SL ;

McCall, CO .

BRITISH JOURNAL OF DERMATOLOGY, 2003, 148 (06) :1242-1244

[3] Exfoliative cheilitis successfully treated with topical tacrolimus [J].

Connolly, M ;

Kennedy, C .

BRITISH JOURNAL OF DERMATOLOGY, 2004, 151 (01) :241-242

[4] Penile lichen sclerosus et atrophicus treated with clobetasol dipropionate 0.05% cream: A retrospective clinical and histopathologic study [J].

Dahlman-Ghozlan, K ;

Hedblad, MA ;

von Krogh, G .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 40 (03) :451-457

[5] Epithelial barrier function and atopic diathesis in rosacea and perioral dermatitis [J].

Dirschka, T ;

Tronnier, H ;

Fölster-Holst, R .

BRITISH JOURNAL OF DERMATOLOGY, 2004, 150 (06) :1136-1141

[6] Safety and Tolerability of Adjuvant Topical Tacrolimus Treatment in Boys with Lichen Sclerosus: A Prospective Phase 2 Study [J].

Ebert, Anne K. ;

Roesch, Wolfgang H. ;

Vogt, Thomas .

EUROPEAN UROLOGY, 2008, 54 (04) :932-937

[7]

Freeman AK, 2004, CUTIS, V73, P267

[8] Tacrolimus ointment for the treatment of steroid-induced rosacea: A preliminary report [J].

Goldman, D .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2001, 44 (06) :995-998

[9] Topical tacrolimus therapy for vitiligio: Therapeutic responses and skin messenger RNA expression of proinflammatory cytokines [J].

Grimes, PE ;

Morris, R ;

Avaniss-Aghajani, E ;

Soriano, T ;

Meraz, M ;

Metzger, A .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2004, 51 (01) :52-61

[10] Multicentre, phase II trial on the safety and efficacy of topical tacrolimus ointment for the treatment of lichen sclerosus [J].

Hengge, U. R. ;

Krause, W. ;

Hofmann, H. ;

Stadler, R. ;

Gross, G. ;

Meurer, M. ;

Brinkmeier, T. ;

Frosch, P. ;

Moll, I. ;

Fritsch, P. ;

Mueller, K. ;

Meykadeh, N. ;

Marini, A. ;

Ruzicka, T. ;

Gollnick, H. .

BRITISH JOURNAL OF DERMATOLOGY, 2006, 155 (05) :1021-1028

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