Pseudo-Multicomponent Reactions of Arynes with N-Aryl Imines

被引：31

作者：

Castillo, Juan-Carlos ^{[1
]}

Quiroga, Jairo ^{[2
]}

Abonia, Rodrigo ^{[2
]}

Rodriguez, Jean ^{[1
]}

Coquerel, Yoann ^{[1
]}

机构：

[1] Aix Marseille Univ, Cent Marseille, CNRS, iSm2 UMR 7313, F-13397 Marseille, France

[2] Univ Valle, Dept Quim, Cali, Colombia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 19期

关键词：

ARYLATION; INSERTION; TANDEM; ANILINES; BENZYNE; ACCESS;

D O I：

10.1021/acs.joc.5b01564

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pseudo-three-component reactions are described for the conversion of simple N-aryl imines into 1,2-dihydroisoquinoline-type products. The approach relies on a regioselective cascade reaction involving two equivalents of the aryne component iteratively as a dienophile and as an electrophile. Some examples of related, more complex pseudo-four-component cascade processes are also reported.

引用

页码：9767 / 9773

页数：7

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