Role of Emerging Environmental Risk Factors in Thyroid Cancer: A Brief Review

被引：127

作者：

Fiore, Maria ^{[1
]}

Conti, Gea Oliveri ^{[1
]}

Caltabiano, Rosario ^{[2
]}

Buffone, Antonino ^{[3
]}

Zuccarello, Pietro ^{[1
]}

Cormaci, Livia ^{[4
]}

Cannizzaro, Matteo Angelo ^{[5
]}

Ferrante, Margherita ^{[1
]}

机构：

[1] Univ Catania, Dept Med Sci Surg & Adv Technol GF Ingrassia, Environm & Food Hyg Labs LIAA, I-95123 Catania, Italy

[2] Dept Med & Surg Sci & Adv Technol GF Ingrassia, Sect Anat Pathol, I-95123 Catania, Italy

[3] Univ Catania, Dept Gen Surg & Specialty Med Surg, Endocrine Surg, AOU Policlin Vittorio Emanuele PO G Rodolico, I-95123 Catania, Italy

[4] Dept Med & Surg Sci & Adv Technol GF Ingrassia, Hyg & Prevent Med Specializaton Sch, I-95123 Catania, Italy

[5] Dept Med & Surg Sci & Adv Technol GF Ingrassia, Chirug Gen, I-95123 Catania, Italy

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2019年 / 16卷 / 07期

关键词：

thyroid; cancer; environment; risk; toxics; ECDs; carcinogenicity; BROMINATED FLAME RETARDANTS; SELENIUM SUPPLEMENTATION; OVARIAN-CANCER; VOLCANIC AREA; AIR-POLLUTION; HEAVY-METALS; EXPOSURE; HEALTH; SERUM; TRIAL;

D O I：

10.3390/ijerph16071185

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Environmental factors are recognized as risk factors of thyroid cancer in humans. Exposure to radiation, both from nuclear weapon or fallout or medical radiation, and to some organic and inorganic chemical toxicants represent a worldwide public health issue for their proven carcinogenicity. Halogenated compounds, such as organochlorines and pesticides, are able to disrupt thyroid function. Polychlorinated biphenyls and their metabolites and polybrominated diethyl ethers bind to thyroid, transport proteins, replace thyroxin, and disrupt thyroid function as phthalates and bisphenolates do, highly mimicking thyroid hormones. A better knowledge of environmental risks represents a very important tool for cancer prevention through true risks prevention and management. This approach is very important because of the epigenetic origin's theory of cancer. Therefore, the aim of this review was study the association between environmental agents and thyroid cancer promotion.

引用

页数：18

共 99 条

[1]

[Anonymous], STATPEARLS

[2]

[Anonymous], EPIDEMIOL PREV

[3]

[Anonymous], TECHN FACT SHEET POL

[4]

[Anonymous], REV ESPANOLA MED NUC

[5] Polybrominated Diphenyl Ethers and Thyroid Cancer Risk in the Prostate, Colorectal, Lung, and Ovarian Cancer Screening Trial Cohort [J].