The Effect of Menopausal Hormone Therapies on Breast Cancer: Avoiding the Risk

被引：8

作者：

Flores, Valerie A. ^{[1
]}

Taylor, Hugh S. ^{[2
]}

机构：

[1] Brown Univ, Women & Infants Hosp, Warren Alpert Med Sch, Providence, RI 02903 USA

[2] Yale Univ, Sch Med, Dept Obstet Gynecol & Reprod Sci, New Haven, CT 06520 USA

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2015年 / 44卷 / 03期

关键词：

Estrogens; Progestogen; Hormone therapy; Breast cancer; Menopause; ESTROGEN PLUS PROGESTIN; CONJUGATED EQUINE ESTROGENS; POSTMENOPAUSAL WOMEN; MEDROXYPROGESTERONE ACETATE; REPLACEMENT THERAPY; MAMMARY-GLAND; GROWTH-FACTOR; SYNTHETIC PROGESTINS; EPITHELIAL-CELLS; HEALTH OUTCOMES;

D O I：

10.1016/j.ecl.2015.05.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Estrogen and progestogen treatment results in greater risk of breast cancer than placebo. Treatment with estrogen alone does not increase the risk of breast cancer, may be used by women who have had a hysterectomy, and may even result in a decreased risk of breast cancer. Continued research seeks to improve the understanding of the interplay between estrogen and progestogens that predispose to adverse effects on breast tissue. Caution over this hypothesized benefit is warranted until it is substantiated by data on the incidence of breast cancer in tissue selective estrogen complex users.

引用

页码：587 / +

页数：17

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