Acute Mastoiditis Before Pneumococcal Vaccination: The Experience of a Large Tertiary Care Pediatric Hospital

被引：4

作者：

Glatstein, Miguel ^{[1
]}

Morag, Sharon ^{[2
]}

Scolnik, Dennis ^{[3
]}

Alper, Arik ^{[2
]}

Reif, Shimon ^{[2
]}

Grisaru-Soen, Galia ^{[4
]}

机构：

[1] Tel Aviv Sourasky Med Ctr, Div Pediat Emergency Med, Dept Pediat, Dana Dwek Children Hosp,Sackler Fac Med, Tel Aviv, Israel

[2] Tel Aviv Sourasky Med Ctr, Dana Dwek Children Hosp, Div Pediat Dept, Sackler Fac Med, Tel Aviv, Israel

[3] Univ Toronto, Hosp Sick Children, Div Pediat Emergency Med & Clin Pharmacol & Toxic, Dept Pediat, Toronto, ON, Canada

[4] Tel Aviv Sourasky Med Ctr, Div Infect Dis, Dana Dwek Childrens Hosp, Sackler Fac Med,Dept Pediat, Tel Aviv, Israel

来源：

AMERICAN JOURNAL OF THERAPEUTICS | 2016年 / 23卷 / 06期

关键词：

acute mastoiditis; pediatric; Streptococcus pneumonia; otitis media; penicillin resistance; SOUTHERN ISRAEL; OTITIS-MEDIA; CHILDREN; ANTIBIOTICS;

D O I：

10.1097/MJT.0000000000000097

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

To report the experience of a large tertiary care pediatric center during a period of increasing Streptococcus pneumoniae antimicrobial resistance before the introduction of pneumococcal vaccine in Israel. Retrospective chart review of children diagnosed acute mastoiditis (AM) between January 1997 and December 2007. The children were divided into 4 age groups (6-11, 12-23, 24-35, and 36-40 months), and each group was compared with the others. A total of 198 AM episodes were recorded during the 10-year study period. The most prevalent pathogen was S. pneumonia, with a very low (15%) penicillin resistance rate (minimal inhibitory concentration 2). Complications were more prevalent in the 12- to 23-month age group. The number of AM cases increased during the study period. Penicillin resistance did not play an important role in determining the morbidity before the introduction of pneumococcal conjugate vaccine.

引用

页码：E1371 / E1374

页数：4

共 18 条

[1] Changes in acute mastoiditis in a single pediatric tertiary medical center: Our experience during 2008-2009 compared with data for 1983-2007 [J].