The ups and downs of nucleic acid duplex stability: Structure-stability studies on chemically modified DNA:RNA duplexes.

被引:0
|
作者
Freier, SM
Altmann, KH
机构
[1] ISIS PHARMACEUT,CARLSBAD,CA 92008
[2] CIBA GEIGY LTD,CENT RES LABS,CH-4002 BASEL,SWITZERLAND
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:385 / COMP
页数:1
相关论文
共 50 条
  • [21] Superior structure stability and selectivity of hairpin nucleic acid probes with an L-DNA stem
    Kim, Youngmi
    Yang, Chaoyong James
    Tan, Weihong
    NUCLEIC ACIDS RESEARCH, 2007, 35 (21) : 7279 - 7287
  • [22] Amide-modified oligonucleotides with preorganized backbone and furanose rings: Highly increased thermodynamic stability of the duplexes formed with their RNA and DNA complements
    DeMesmaeker, A
    Lebreton, J
    Jouanno, C
    Fritsch, V
    Wolf, RM
    Wendeborn, S
    SYNLETT, 1997, (11) : 1287 - 1290
  • [23] Analogues of a locked nucleic acid with three-carbon 2′,4′-linkages:: Synthesis by ring-closing metathesis and influence on nucleic acid duplex stability and structure
    Albaek, Nanna
    Petersen, Michael
    Nielsen, Poul
    JOURNAL OF ORGANIC CHEMISTRY, 2006, 71 (20): : 7731 - 7740
  • [24] Comparison of Intrinsic Stacking Energies of Ten Unique Dinucleotide Steps in A-RNA and B-DNA Duplexes. Can We Determine Correct Order of Stability by Quantum-Chemical Calculations?
    Svozil, Daniel
    Hobza, Pavel
    Sponer, Jiri
    JOURNAL OF PHYSICAL CHEMISTRY B, 2010, 114 (02): : 1191 - 1203
  • [25] NMR studies of fully modified locked nucleic acid (LNA) hybrids:: Solution structure of an LNA:RNA hybrid and characterization of an LNA:DNA hybrid
    Nielsen, KE
    Rasmussen, J
    Kumar, R
    Wengel, J
    Jacobsen, JP
    Petersen, M
    BIOCONJUGATE CHEMISTRY, 2004, 15 (03) : 449 - 457
  • [26] Replacement of the phosphodiester linkage in oligonucleotides by heterocycles: The effect of triazole- and imidazole-modified backbones on DNA/RNA duplex stability
    vonMatt, P
    Altmann, KH
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1997, 7 (12) : 1553 - 1556
  • [27] Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability
    Gilbert, Jennifer
    Sebastiani, Federica
    Arteta, Marianna Yanez
    Terry, Ann
    Fornell, Anna
    Russell, Robert
    Mahmoudi, Najet
    Nylander, Tommy
    JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2024, 660 : 66 - 76
  • [28] Molecular-dynamics studies of single-stranded hexitol, altritol, mannitol, and ribose nucleic acids (HNA, MNA, ANA, and RNA, resp,) and of the stability of HNA•RNA, ANA•RNA, and MNA•RNA duplexes
    Froeyen, M
    Wroblowski, B
    Esnouf, R
    De Winter, H
    Allart, B
    Lescrinier, E
    Herdewijn, P
    HELVETICA CHIMICA ACTA, 2000, 83 (09) : 2153 - 2182
  • [29] STUDIES ON NUCLEIC ACIDS .8. CHANGES IN STABILITY OF DNA SECONDARY STRUCTURE BY INTERACTION WITH DIVALENT METAL IONS
    VENNER, H
    ZIMMER, C
    BIOPOLYMERS, 1966, 4 (03) : 321 - &
  • [30] Insights into the structural features and stability of peptide nucleic acid with a D-prolyl-2-aminocyclopentane carboxylic acid backbone that binds to DNA and RNA
    Poomsuk, Nattawee
    Vilaivan, Tirayut
    Siriwong, Khatcharin
    JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2018, 84 : 36 - 42