Chemical Analysis, Cytotoxicity and Antimicrobial Studies by Snapdragon: A Medicinal Plant

被引:9
作者
Riaz, Muhammad [1 ]
Rasool, Nasir [1 ]
Rasool, Shahid [2 ]
Rashid, Umer [3 ]
Bukhari, Iftikhar Hussain [1 ]
Zubair, Muhammad [1 ]
Noreen, Mnaza [1 ]
Abbas, Mazhar [4 ]
机构
[1] Govt Coll Univ, Dept Chem, Faisalabad 38000, Pakistan
[2] Univ Sargodha, Fac Pharm, Sargodha 40100, Pakistan
[3] Univ Putra Malaysia, Inst Adv Technol, Upm Serdang 43400, Selangor, Malaysia
[4] Univ Agr Faisalabad, Dept Chem & Biochem, Faisalabad 38040, Pakistan
关键词
Snapdragon; Antimicrobial activity; Cytotoxicity; GC-MS; HPLC; GC-MS ANALYSIS; ANTIOXIDANT; WILD;
D O I
10.14233/ajchem.2013.14854
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this work, we evaluated the antimicrobial, cytotoxicity properties of the snapdragon (Antirrhinum majus) extract and fractions. The cytotoxicity, studied by haemolytic activity against human blood erythrocytes assays, indicated a low cytotoxic effect on the absolute methanol extract and its fractions from plant. Chemical analysis of whole plant was also carried out. For chemical analysis HP-LC analysis was carried out to determine the presence of phenolics. The GC-MS analysis was also carried out to determine the presence of some phytoconstituents in n-hexane extract (extracted by soxhlet). The results of present study revealed that snapdragon plant might be considered as a good source of natural antimicrobial.
引用
收藏
页码:5479 / 5482
页数:4
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